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Dasatinib 100 mg once daily minimizes the occurrence of pleural effusion in patients with chronic myeloid leukemia in chronic phase and efficacy is unaffected in patients who develop pleural effusion†
Article first published online: 18 NOV 2009
DOI: 10.1002/cncr.24734
Copyright © 2009 American Cancer Society
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How to Cite
Porkka, K., Khoury, H. J., Paquette, R. L., Matloub, Y., Sinha, R. and Cortes, J. E. (2010), Dasatinib 100 mg once daily minimizes the occurrence of pleural effusion in patients with chronic myeloid leukemia in chronic phase and efficacy is unaffected in patients who develop pleural effusion. Cancer, 116: 377–386. doi: 10.1002/cncr.24734
- †
David Dejardin (Bristol-Myers Squibb) provided assistance with statistical analysis.
Publication History
- Issue published online: 20 JAN 2010
- Article first published online: 18 NOV 2009
- Manuscript Accepted: 4 MAY 2009
- Manuscript Revised: 21 APR 2009
- Manuscript Received: 13 FEB 2009
Funded by
- Funding for the clinical trial, statistical analysis, and medical writing assistance was provided by Bristol-Myers Squibb (BMS)
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- 2, , , , Reversible pulmonary arterial hypertension likely related to long-term, low-dose dasatinib treatment for chronic myeloid leukaemia, Leukemia Research, 2012, 36, 1, e4
- 3, , , , , Treatment options for chronic myeloid leukemia, Expert Opinion on Pharmacotherapy, 2012, 13, 6, 815
- 4, , Activity and Safety of Dasatinib as Second-Line Treatment or in Newly Diagnosed Chronic Phase Chronic Myeloid Leukemia Patients, BioDrugs, 2011, 25, 3, 147
- 5, , , Development of an Effective Therapy for Chronic Myelogenous Leukemia, The Cancer Journal, 2011, 17, 6, 477
- 6, , Prevalence of large granular lymphocytosis in patients with chronic myelogenous leukemia (CML) treated with dasatinib, Leukemia Research, 2011, 35, 1, e1
- 7, , , , , , Clinical features of dasatinib-induced large granular lymphocytosis and pleural effusion, International Journal of Hematology, 2010, 91, 5, 799
- 8, , , , , , , , , , , , , , , , , , , , Dasatinib versus Imatinib in Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia, New England Journal of Medicine, 2010, 362, 24, 2260
- 9, , , , , , , Empfehlungen zur Verlaufskontrolle und Zweitlinientherapie bei der chronischen myeloischen Leukämie (CML), Der Onkologe, 2010, 16, 7, 701
- 10, , , Management of adverse events associated with tyrosine kinase inhibitors in the treatment of chronic myeloid leukemia, Leukemia, 2010, 25, 2, 201
- 11, , Pleural effusions due to dasatinib, Current Opinion in Pulmonary Medicine, 2010, 16, 4, 351

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