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Nurses provide valuable proxy assessment of the health-related quality of life of children with Hodgkin disease†
Version of Record online: 3 FEB 2010
Copyright © 2010 American Cancer Society
Volume 116, Issue 6, pages 1602–1607, 15 March 2010
How to Cite
Klaassen, R. J., Barr, R. D., Hughes, J., Rogers, P., Anderson, R., Grundy, P., Ali, S. K., Yanofsky, R., Abla, O., Silva, M., Carret, A.-S. and Cappelli, M. (2010), Nurses provide valuable proxy assessment of the health-related quality of life of children with Hodgkin disease. Cancer, 116: 1602–1607. doi: 10.1002/cncr.24888
We thank the many nurses who helped out with this study, including Deanna Lawson, Maryanne Gibson and Catherine Bourne. We would like to acknowledge Dr. Isabelle Gaboury, Dr. Murray Krahn, Dr. Lawrence Jardine, and Dr. Dorothy Barnard for their contributions as coauthors.
- Issue online: 3 MAR 2010
- Version of Record online: 3 FEB 2010
- Manuscript Accepted: 23 JUL 2009
- Manuscript Revised: 20 JUL 2009
- Manuscript Received: 1 JUN 2009
- quality of life;
- Hodgkin disease;
We prospectively compared the proxy reporting of health-related quality of life (HRQL) by parents and nurses of children with Hodgkin disease to see how well they correlated with the children's report.
Children with all stages of Hodgkin disease, their parents, and the clinic nurse were all asked to complete 4 different HRQL measures at 4 time points: 2 weeks after the first course of chemotherapy, on the third day of the second course of chemotherapy, during the third week of radiation, and 1 year after diagnosis.
Fifty-one patients from 12 centers across Canada were enrolled in the study between May 1, 2002 and March 31, 2005. Two patients were excluded. The children's Pediatric Quality of Life Inventory (PedsQL) generic scores increased from 64 at base line to 81 at the end of the study. There was substantial agreement (intraclass correlation coefficient >0.6) among the participants' scores at most time points except when the child was actively receiving inpatient chemotherapy. At that time, there was only fair to moderate agreement between the child and parent, with the parents on average rating the PedsQL generic score 5 points lower than the child. The nurses still had substantial agreement at that time point with the PedsQL generic and cancer module as well as the EuroQol EQ-5D visual analogue scale visual analogue scale.
Over the course of treatment for Hodgkin disease, there was substantial agreement among the parent's, nurse's, and children's reported HRQL scores. Nurses contribute valuable additional information as proxy respondents. Cancer 2010. © 2010 American Cancer Society.