Angiogenesis, lymphangiogenesis, growth pattern, and tumor emboli in inflammatory breast cancer

A review of the current knowledge

Authors

  • Peter B. Vermeulen MD, PhD,

    Corresponding author
    1. Translational Cancer Research Group and Pathology Department, Cancer Center of the Saint-Augustinus Hospital, University of Antwerp, Wilrijk, Belgium
    • Translational Cancer Research Group, University of Antwerp/University Hospital Antwerp, Oncology Center, General Hospital, St.-Augustinus, Wilrijk, Antwerp, 2610, Belgium
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    • Fax: (011) 3234433019

  • Kenneth L. van Golen PhD,

    1. Department of Biological Sciences, University of Delaware, Newark, Delaware
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  • Luc Y. Dirix MD, PhD

    1. Translational Cancer Research Group and Pathology Department, Cancer Center of the Saint-Augustinus Hospital, University of Antwerp, Wilrijk, Belgium
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  • The articles in this supplement were presented at the First International Inflammatory Breast Cancer Conference, Houston, Texas, December 5-7, 2008.

Abstract

This objective of the current review was to provide the reader with a comprehensive summary of the literature related to 3 important and inter-related features of the biology of inflammatory breast cancer (IBC): angiogenesis, lymphangiogenesis, and the formation of tumor emboli. Information derived from animal models of IBC as well as from translational studies using tissue samples of patients with IBC are discussed. Cancer 2010;116(11 suppl):2748–54. © 2010 American Cancer Society.

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