Bringing the p53 signature into focus

Authors

  • Christopher P. Crum MD,

    Corresponding author
    1. Department of Pathology, Division of Women's and Perinatal Pathology, Brigham and Women's Hospital, Boston, Massachusetts
    • Department of Pathology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115
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    • Fax: (617) 264-5125

  • Wa Xian PhD

    1. Department of Pathology, Division of Women's and Perinatal Pathology, Brigham and Women's Hospital, Boston, Massachusetts
    2. Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Singapore
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  • See referenced original article on pages 5261-71, this issue.

Abstract

The p53 signature is emerging as an important precursor to pelvic cancer. In this issue of Cancer, a report from investigators at the University of Washington School of Medicine adds important data in support of this concept in women with familial ovarian cancer.

Ancillary