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Phosphorylated AKT expression is associated with PIK3CA mutation, low stage, and favorable outcome in 717 colorectal cancers

  1. Yoshifumi Baba MD1,†,
  2. Katsuhiko Nosho MD1,†,
  3. Kaori Shima PhD1,†,
  4. Marika Hayashi BS1,
  5. Jeffrey A. Meyerhardt MD1,
  6. Andrew T. Chan MD2,
  7. Edward Giovannucci MD3,4,
  8. Charles S. Fuchs MD1,4,
  9. Shuji Ogino MD1,5,‡,*

Article first published online: 8 NOV 2010

DOI: 10.1002/cncr.25630

Issue

Cancer

Cancer

Volume 117, Issue 7, pages 1399–1408, 1 April 2011

Additional Information

How to Cite

Baba, Y., Nosho, K., Shima, K., Hayashi, M., Meyerhardt, J. A., Chan, A. T., Giovannucci, E., Fuchs, C. S. and Ogino, S. (2011), Phosphorylated AKT expression is associated with PIK3CA mutation, low stage, and favorable outcome in 717 colorectal cancers. Cancer, 117: 1399–1408. doi: 10.1002/cncr.25630

Author Information

  1. 1

    Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts

  2. 2

    Gastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts

  3. 3

    Department of Epidemiology and Nutrition, Harvard School of Public Health, Boston, Massachusetts

  4. 4

    Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts

  5. 5

    Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts

  1. †

    Y.B., K.N., and K.S. contributed equally.

  2. ‡

    Fax: (617) 277-9015

*Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, 44 Binney St., Room JF-215C, Boston, MA 02115

Publication History

  1. Issue published online: 18 MAR 2011
  2. Article first published online: 8 NOV 2010
  3. Manuscript Accepted: 3 AUG 2010
  4. Manuscript Revised: 28 JUL 2010
  5. Manuscript Received: 1 JUL 2010

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