Reply to assessment of capsular melanoma cell deposits in sentinel lymph nodes
Article first published online: 24 JAN 2011
Copyright © 2011 American Cancer Society
Volume 117, Issue 12, page 2821, 15 June 2011
How to Cite
Meier, A., Satzger, I., Völker, B., Kapp, A. and Gutzmer, R. (2011), Reply to assessment of capsular melanoma cell deposits in sentinel lymph nodes. Cancer, 117: 2821. doi: 10.1002/cncr.25789
- Issue published online: 7 JUN 2011
- Article first published online: 24 JAN 2011
- Manuscript Accepted: 27 SEP 2010
- Manuscript Received: 3 SEP 2010
We appreciate the interest in our article1 expressed by Drs. Bertsch and Kretschmer, as they have raised 2 interesting points. We defined capsular invasion as presence of melanoma cells in the capsule of the sentinel lymph node (SLN). This might have different reasons, and we agree with Dr. Bertsch that further research is necessary to better define this feature, which could result in defined subgroups as suggested by Dr. Bertsch. Furthermore, we appreciate the comment of Dr. Bertsch that in his patient also, collective capsular invasion of the melanoma SLN is of prognostic importance, substantiating our findings in another independent group of patients.
- 1Comparison of classification systems in melanoma sentinel lymph nodes: an analysis of 697 patients from a single center. Cancer. 2010; 116: 3178-3188., , , . .