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Article first published online: 26 APR 2011
Copyright © 2011 American Cancer Society
Supplement: Adolescents and Young Adults with Cancer: Towards Better Outcomes in Canada
Volume 117, Issue Supplement 10, pages 2301–2310, 15 May 2011
How to Cite
Wallace, W. H. B. (2011), Oncofertility and preservation of reproductive capacity in children and young adults. Cancer, 117: 2301–2310. doi: 10.1002/cncr.26045
Some of the ideas and thoughts presented in this review have been published in review articles authored or coauthored by the author.
The articles in this supplement represent presentations and discussions at the “International Workshop on Adolescents and Young Adults with Cancer: Towards Better Outcomes in Canada” that was held in Toronto, Ontario, March 11-13, 2010.
*Workshop on Adolescents and Young Adults with Cancer: Towards Better Outcomes in Canada, Supplement to Cancer.
- Issue published online: 26 APR 2011
- Article first published online: 26 APR 2011
- Manuscript Accepted: 10 DEC 2010
- Manuscript Revised: 8 DEC 2010
- Manuscript Received: 20 SEP 2010
- fertility preservation
With increasing numbers of survivors from cancer at a young age, the issue of fertility preservation has assumed greater importance. This review describes normal ovarian and testicular function and summarizes what is known about the effect of chemotherapy and radiotherapy on the gonads and uterus. All young patients with cancer or leukemia should have their fertility prognosis discussed before the initiation of treatment. Sperm and embryo cryopreservation should be considered standard practice and be widely available for those at significant risk of infertility. For prepubertal girls, ovarian tissue cryopreservation should be considered if the risk of premature menopause is high, but for the prepubertal boy there are no established techniques in current practice. Cancer 2011;117(10 suppl):2301–10. © 2011 American Cancer Society.