Nativity and papillary thyroid cancer incidence rates among Hispanic women in California

Authors

  • Pamela L. Horn-Ross PhD,

    Corresponding author
    1. Cancer Prevention Institute of California, Fremont, California
    2. Department of Health Research and Policy and Stanford Cancer Center, Stanford University School of Medicine, Palo Alto, California
    • Cancer Prevention Institute of California, 2201 Walnut Ave., Suite 300, Fremont, CA 94538

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    • Fax: (510) 608-5085

  • Ellen T. Chang ScD,

    1. Cancer Prevention Institute of California, Fremont, California
    2. Department of Health Research and Policy and Stanford Cancer Center, Stanford University School of Medicine, Palo Alto, California
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  • Christina A. Clarke PhD,

    1. Cancer Prevention Institute of California, Fremont, California
    2. Department of Health Research and Policy and Stanford Cancer Center, Stanford University School of Medicine, Palo Alto, California
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  • Theresa H. M. Keegan PhD,

    1. Cancer Prevention Institute of California, Fremont, California
    2. Department of Health Research and Policy and Stanford Cancer Center, Stanford University School of Medicine, Palo Alto, California
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  • Rudolph P. Rull PhD,

    1. Cancer Prevention Institute of California, Fremont, California
    2. Department of Health Research and Policy and Stanford Cancer Center, Stanford University School of Medicine, Palo Alto, California
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  • Thu Quach PhD,

    1. Cancer Prevention Institute of California, Fremont, California
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  • Scarlett Lin Gomez PhD

    1. Cancer Prevention Institute of California, Fremont, California
    2. Department of Health Research and Policy and Stanford Cancer Center, Stanford University School of Medicine, Palo Alto, California
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  • We thank Tim Miller, Rita Leung, Sarah Shema, Jane Pham, Laura McClure, and Kari Fish for help with the compilation of data.

  • The ideas and opinions expressed herein are those of the authors; endorsement by the State of California, the California Department of Health Services, the National Cancer Institute, or the Centers for Disease Control and Prevention or their contractors and subcontractors is not intended and should not be inferred.

Abstract

BACKGROUND:

Overall, the incidence of papillary thyroid cancer in Hispanic women residing in the United States (US) is similar to that of non-Hispanic white women. However, little is known as to whether rates in Hispanic women vary by nativity, which may influence exposure to important risk factors.

METHODS:

Nativity-specific incidence rates among Hispanic women were calculated for papillary thyroid cancer using data from the California Cancer Registry (CCR) for the period 1988-2004. For the 35% of cases for whom birthplace information was not available from the CCR, nativity was statistically imputed based on age at Social Security number issuance. Population estimates were extracted based on US Census data. Incidence rate ratios (IRRs) and 95% confidence intervals (CIs) were also estimated.

RESULTS:

In young (age <55 years) Hispanic women, the incidence of papillary thyroid cancer among US-born women (10.65 per 100,000) was significantly greater than that for foreign-born women (6.67 per 100,000; IRR, 1.60 [95% CI, 1.44-1.77]). The opposite pattern was observed in older women. The age-specific patterns showed marked differences by nativity: among foreign-born women, rates increased slowly until age 70 years, whereas among US-born women, incidence rates peaked during the reproductive years. Incidence rates increased over the study period in all subgroups.

CONCLUSION:

Incidence rates of papillary thyroid cancer vary by nativity and age among Hispanic women residing in California. These patterns can provide insight for future etiologic investigations of modifiable risk factors for this increasingly common and understudied cancer. Cancer 2012;. © 2011 American Cancer Society.

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