Original Article

Predicting the risk of chemotherapy toxicity in older patients: The Chemotherapy Risk Assessment Scale for High-Age Patients (CRASH) score†

  1. Martine Extermann MD1,*,
  2. Ivette Boler ARNP1,
  3. Richard R. Reich PhD1,2,
  4. Gary H. Lyman MD3,
  5. Richard H. Brown MD4,
  6. Joseph DeFelice MD5,‡,
  7. Richard M. Levine MD6,
  8. Eric T. Lubiner MD7,
  9. Pablo Reyes MD8,
  10. Frederic J. Schreiber III MD9,
  11. Lodovico Balducci MD1

Article first published online: 9 NOV 2011

DOI: 10.1002/cncr.26646

Additional Information

How to Cite

Extermann, M., Boler, I., Reich, R. R., Lyman, G. H., Brown, R. H., DeFelice, J., Levine, R. M., Lubiner, E. T., Reyes, P., Schreiber, F. J. and Balducci, L. (2011), Predicting the risk of chemotherapy toxicity in older patients: The Chemotherapy Risk Assessment Scale for High-Age Patients (CRASH) score. Cancer. doi: 10.1002/cncr.26646

Author Information

  1. 1

    Senior Adult Oncology Program, Moffitt Cancer Center, University of South Florida, Tampa, Florida

  2. 2

    College of Arts and Sciences, University of South Florida Sarasota-Manatee, Sarasota, Florida

  3. 3

    Duke Center for Clinical Health Policy Research, Duke University, Durham, North Carolina

  4. 4

    Sarasota Memorial Hospital, Sarasota, Florida

  5. 5

    Morton Plant Hospital, St. Petersburg, Florida

  6. 6

    Space Coast Medical Associates, Titusville, Florida

  7. 7

    Fawcet Memorial Hospital, Port Charlotte, Florida

  8. 8

    Leesburg Regional Hospital, Leesburg, Florida

  9. 9

    Watson Clinic, Lakeland, Florida

  1. ‡

    Deceased.

*Senior Adult Oncology Program, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, Tampa, FL 33612

  1. †

    We thank Anna Davis, Jyoti Dubey, Tammy Green, and Ellie O'Neil, for their support in creating and managing the study database.

Publication History

  1. Article first published online: 9 NOV 2011
  2. Manuscript Accepted: 14 SEP 2011
  3. Manuscript Revised: 13 SEP 2011
  4. Manuscript Received: 15 AUG 2011

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