• 1
    Weiser MR, Landmann RG, Kattan MW, et al. Individualized prediction of colon cancer recurrence using a nomogram. J Clin Oncol. 2008; 26: 380-385.
  • 2
    American Joint Committee on Cancer (AJCC). Colon and rectum. In: Edge SB, Byrd DR, Compton CC, eds. AJCC Cancer Staging Manual. 7th ed. New York: Springer; 2010: 143-164.
  • 3
    Lines LM, Lang K, Lee DW, et al. Trends in stage distribution and survival among elderly colorectal cancer patients in the US [abstract]. J Clin Oncol. 2008; 26( May 20 suppl). Abstract 4043.
  • 4
    National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines in Oncology (NCCN Guidelines)—Colon Cancer (V1.2012) and Rectal Cancer (V1.2012). Available at: Accessed October 10, 2011.
  • 5
    Obrand DI, Gordan PH. Incidence and patterns of recurrence following curative resection for colorectal carcinoma. Dis Colon Rectum. 1997; 40: 15-24.
  • 6
    van Leerdam ME, Smyrk TC, Enders F, Holton S, De Groen PC. Long term outcome of early colorectal cancer treated with local excision or radical resection [abstract]. Gastroenterology. 2010; 138( 5 suppl 1): S44. Abstract 230.
  • 7
    Lin C-C, Lin J-K, Chang S-C, et al. Is adjuvant chemotherapy beneficial to high-risk stage II colon cancer? Analysis in a single institute. Int J Colorectal Dis. 2009; 24: 665-676.
  • 8
    Mitra AP, Almal AA, George B, et al. The use of genetic programming in the analysis of quantitative gene expression profiles for identification of nodal status in bladder cancer [serial online]. BMC Cancer. 2006; 6: 159. Available at: Accessed October 10, 2011.
  • 9
    Yu J, Yu J, Almal AA, et al. Feature selection and molecular classification of cancer using genetic programming. Neoplasia. 2007; 9: 292-303.
  • 10
    Petersen VC, Baxter KJ, Love SB, Shepherd NA. Identification of objective pathological prognostic determinants and models of prognosis in Dukes B colon cancer. Gut. 2002; 51: 65-69.
  • 11
    Blanke CD. Perforation and stage II colon cancer: is it always high-risk? Gastrointest Cancer Res. 2008; 2: 103-104.
  • 12
    Katoh H, Yamashita K, Wqang G, Sato T, Nakamura T, Watanabe M. Prognostic significance of preoperative bowel obstruction in stage III colorectal cancer. Ann Surg Oncol. 2011; 18: 2432-2441.
  • 13
    Serpell JW, McDermott FT, Katrivessis H, Hughes ESR. Obstructing carcinomas of the colon. Br J Surg. 1989; 76: 965-969.
  • 14
    Harris EI, Lewin DN, Wang HL, et al. Lymphovascular invasion in colorectal cancer: an interobserver variability study. Am J Surg Pathol. 2008; 32: 1816-1821.
  • 15
    Liebig C, Ayala G, Wilks J, et al. Perineural invasion is an independent predictor of outcome in colorectal cancer. J Clin Oncol. 2009; 27: 5131-5137.
  • 16
    Kulendran M, Stebbing JF, Marks CG, Rockall TA. Predictive and prognostic factors in colorectal cancer: a personalized approach [serial online]. Cancers. 2011; 3: 1622-1638.
  • 17
    Gray RG, Quirke P, Handley K, et al. Validation study of a quantitative multigene reverse transcriptase-polymerase chain reaction assay for assessment of recurrence risk in patients with stage II colon cancer. J Clin Oncol. 2011; 29: 4611-4619.