Treatment of early-stage prostate cancer among rural and urban patients
Version of Record online: 13 JUN 2013
Copyright © 2013 American Cancer Society
Volume 119, Issue 16, pages 3067–3075, 15 August 2013
How to Cite
Baldwin, L.-M., Andrilla, C. H. A., Porter, M. P., Rosenblatt, R. A., Patel, S. and Doescher, M. P. (2013), Treatment of early-stage prostate cancer among rural and urban patients. Cancer, 119: 3067–3075. doi: 10.1002/cncr.28037
- Issue online: 2 AUG 2013
- Version of Record online: 13 JUN 2013
- Manuscript Accepted: 3 JAN 2013
- Manuscript Revised: 23 DEC 2012
- Manuscript Received: 23 AUG 2012
- prostatic neoplasms;
- rural population;
- health care quality, access, and evaluation;
- SEER Program
Geographic barriers and limited availability of cancer specialists may influence early prostate cancer treatment options for rural men. This study compares receipt of different early prostate cancer treatments between rural and urban patients.
Using 2004-2006 SEER Limited-Use Data, 51,982 early prostate cancer patients were identified (T1c, T2a, T2b, T2c, T2NOS; no metastases) who were most likely to benefit from definitive treatment (< 75 years old, Gleason score < 8, PSA ≤ 20). Definitive treatment included radical prostatectomy, daily external beam radiation for 5 to 8 weeks, brachytherapy, or combination external beam radiation/brachytherapy. Adjusted definitive treatment rates were calculated by rural–urban residence overall, and for different sociodemographic and cancer characteristics, and different states based on logistic regression analyses, using general estimating equation methods to account for clustering by county.
Adjusted definitive treatment rates were lower for rural (83.7%) than urban (87.1%) patients with early-stage prostate cancer (P ≤ .01). Rural men were more likely than urban men to receive nondefinitive surgical treatment and no initial treatment. The lowest definitive treatment rates were among rural subgroups: 70 to 74 years (73.9%), African Americans (75.6%), American Indians/Alaska Natives (77.8%), single/separated/divorced (76.8%), living in New Mexico (69.3%), and living in counties with persistent poverty (79.6%).
Between 2004 and 2006, this adjusted analysis found that men who were living in rural areas were less likely to receive definitive treatment for their early-stage prostate cancer than those living in urban areas. Certain rural patient groups with prostate cancer need particular attention to ensure their access to appropriate treatment. Rural providerss, rural health care systems, and cancer advocacy and support organizations should ensure resources are in place so that the most vulnerable rural groups (men between 60 and 74 years of age; African American men; men who are single, separated, or divorced; and men living in rural New Mexico) can make informed prostate cancer treatment choices based on their preferences. Cancer 2013;119:3067—3075. © 2013 American Cancer Society.