European-American Dialogues on Cancer Survivorship: Current Perspectives and Emerging Issues
Cancer-related fatigue and its impact on functioning
Article first published online: 20 MAY 2013
Copyright © 2013 American Cancer Society
Supplement: European-American Dialogues on Cancer Survivorship: Current Perspectives and Emerging Issues
Volume 119, Issue Supplement S11, pages 2124–2130, 1 June 2013
How to Cite
Minton, O., Berger, A., Barsevick, A., Cramp, F., Goedendorp, M., Mitchell, S. A. and Stone, P. C. (2013), Cancer-related fatigue and its impact on functioning. Cancer, 119: 2124–2130. doi: 10.1002/cncr.28058
This supplement was guest edited by Vittorio Mattioli, MD (NCRC, Bari, Italy) and Kevin Stein, PhD (American Cancer Society, Atlanta, Georgia) and was produced with the authoritative contribution of 58 authors from the European Union and the United States. The primary aims are to highlight the potential differences between European and American approaches to cancer survivors&apos issues, increase coordination among oncologists and other primary care providers, and aid the development of a shared care model that can improve the quality of cancer care.
The opinions or views expressed in this supplement are those of the authors and do not necessarily reflect the opinions or recommendations of the journal editors, the American Cancer Society, John Wiley & Sons Inc, or the National Cancer Research Centre Istituto Tumori “Giovanni Paolo II” Bari.
The first 2 authors are the joint lead coauthors for this article.
- Issue published online: 20 MAY 2013
- Article first published online: 20 MAY 2013
- Manuscript Accepted: 20 DEC 2012
- Manuscript Revised: 19 DEC 2012
- Manuscript Received: 27 JUL 2012
- cancer-related fatigue;
This article presents the contrasting European and American perspectives on cancer-related fatigue (CRF) and its impact on functioning in cancer survivors. The content is presented in 3 sections: state of the art, intervention studies, and future areas of research, followed by a discussion. Gaps identified include a lack of understanding of the etiology, definition, and measurement of CRF. Models to guide the study of CRF, selection of biomarkers, and design of interventions are needed. There is overlap between Europe and the United States concerning the future directions for research and collaboration related to CRF. The authors suggest the need for international consensus regarding the defining features of CRF in cancer survivors to identify phenotypes, a harmonized measurement of CRF outcomes using instruments that have demonstrated measurement equivalence across languages and cultures, and interventions (including exercise, rehabilitation, and psychoeducational) that have been manualized to permit intervention fidelity across diverse contexts. Coordinated intercontinental efforts would increase understanding of the biological, psychological, and social mechanisms underlying CRF and assist in the design of future intervention studies as well as revisions to clinical guidelines. Cancer 2013;119(11 suppl):2124-30. © 2013 American Cancer Society.