Unusual intracardiac tumor in a child: Inflammatory pseudotumor or “granulomatous” variant of myxoma?

Authors

  • F. Gonzalez-Crussi MD,

    Associate Professor of Pathology, Corresponding author
    1. Department of Pathology, Indiana University, School of Medicine, Indianapolis, IN
    • Department of Pathology, 1100 W. Michigan Street, Indianapolis, IN 46202
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  • Burton L. Vanderbilt BA,

    2nd-year Medical Student
    1. Department of Pathology, Indiana University, School of Medicine, Indianapolis, IN
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  • Jon K. Miller MD

    Senior Resident
    1. Anatomical Pathology
    2. Department of Pathology, Indiana University, School of Medicine, Indianapolis, IN
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Abstract

An intracardiac tumor arising in the right atrium of a young child is reported. Morphologically, the lesion was reminiscent of “plasma cell granulomas,” but unprecedented in this location. Based on clinical manifestations, laboratory findings, histologic and ultrastructural characteristics of the mass, the speculation is put forth that this lesion may represent a cardiac myxoma with atypical structural features. An extension of this proposal is a pathogenetic sequence that would try to reconcile the complex clinical course of some myxomas with the described structural observations. Alternative choices for classification of the lesion are also given consideration.

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