Physical, emotional, and social health differences between posttreatment young adults with cancer and matched healthy controls
Article first published online: 28 MAY 2014
© 2014 American Cancer Society
Volume 120, Issue 15, pages 2247–2254, August 1, 2014
How to Cite
Salsman, J. M., Garcia, S. F., Yanez, B., Sanford, S. D., Snyder, M. A. and Victorson, D. (2014), Physical, emotional, and social health differences between posttreatment young adults with cancer and matched healthy controls. Cancer, 120: 2247–2254. doi: 10.1002/cncr.28739
- Issue published online: 21 JUL 2014
- Article first published online: 28 MAY 2014
- Manuscript Accepted: 3 JAN 2014
- Manuscript Revised: 18 NOV 2013
- Manuscript Received: 23 JUL 2013
- quality of life;
- young adults;
- controlled comparison study;
- posttraumatic growth
Young adults (YAs; ages 18-39 years) with cancer face interrupted developmental milestones and increased stressors that can adversely influence psychosocial adjustment. Transitioning from active treatment to posttreatment survivorship can be particularly challenging. The purpose of this study is to describe the health-related quality of life (HRQL) and psychological adaptation of YAs after treatment, relative to young adults without cancer.
Three cohorts of YAs of mixed cancer diagnoses (N = 120, 0-12 months after treatment; N = 102, 13-24 months after treatment; and N = 113, 25-60 months after treatment; combined M = 31.8 years old, combined sex = 68% women) and an age-, education-, sex-, and partner status–matched group of healthy control participants (HCs; N = 335) were recruited via an online research panel. All participants completed measures assessing demographic and clinical characteristics, HRQL (physical, emotional, social, and spiritual), and psychological adaptation (anxiety, depression, positive affect, posttraumatic growth). Measure content was slightly modified for applicability to HCs without a cancer history.
Multivariate analysis of covariance found a significant main effect for group (YAs versus HCs) and a significant group-by-cohort interaction. YAs reported poorer physical (P = .005, d = .22) and emotional well-being (P = .011, d = .20) but better social well-being (P < .001, d = .49). YAs reported comparatively stable scores (P = .74) for posttraumatic growth compared to HCs, who reported greater posttraumatic growth across cohorts (P = .01, d = 16).
Findings underscore the negative and positive sequelae for YAs and highlight the need for comprehensive assessment among YA survivors of cancer. A matched, HC group allows the HRQL and psychological adaptation of YAs to be placed in context, enabling a more precise determination of the impact of cancer on YAs. Cancer 2014;120:2247–2254. © 2014 American Cancer Society.