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Cancer Cytopathology

Cover image for Cancer Cytopathology

25 February 2004

Volume 102, Issue 1

Pages 1–65

Currently known as: Cancer Cytopathology

  1. Original Articles

    1. Top of page
    2. Original Articles
    3. Original Artcles
    4. Original Articles
    1. Gynecologic Cytopathology

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      Cytology of human ovarian surface epithelial brushings (pages 1–10)

      Santo V. Nicosia, George D. Wilbanks, Beatriz Saunders, James Mayer, Richard J. Cardosi, Patricia A. Kruk, Jin Cheng, Wenlong Bai, Domenico Coppola and James Fiorica

      Version of Record online: 23 DEC 2003 | DOI: 10.1002/cncr.20001

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      The current study defined baseline features of human ovarian surface epithelial (HOSE) cells. The authors demonstrated that HOSE cells are important to pathologists and clinicians evaluating women at risk for ovarian epithelial cancer and to researchers investigating the pathobiology of this aggressive gynecologic malignancy.

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      Comparison of hybrid capture 2 with in situ hybridization for the detection of high-risk human papillomavirus in liquid-based cervical samples (pages 11–18)

      Albertus T. Hesselink, Adriaan J. C. van den Brule, Antoinette A. T. P. Brink, Johannes Berkhof, Folkert J. van Kemenade, René H. M. Verheijen and Peter J. F. Snijders

      Version of Record online: 11 DEC 2003 | DOI: 10.1002/cncr.11904

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      Hybrid Capture 2 and in situ hybridization (ISH) assays were compared to detect high-risk human papillomavirus in liquid-based preparations of cervical scrapings. Although positive ISH results are associated with an increased overall viral load in the sample, the analytic sensitivity of ISH is too low to detect all women with prevalent, high-grade cervical intraepithelial neoplasia.

  2. Original Artcles

    1. Top of page
    2. Original Articles
    3. Original Artcles
    4. Original Articles
    1. Non-Gynecologic Cytopathology

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      Anorectal cytology as a screening tool for anal squamous lesions : Cytologic, anoscopic, and histologic correlation (pages 19–26)

      Maria A. Friedlander, Elizabeth Stier and Oscar Lin

      Version of Record online: 9 DEC 2003 | DOI: 10.1002/cncr.11888

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      Anorectal cytology is an accurate method for screening for anal squamous lesions; however, atypical parakeratotic cells represent a potential pitfall. Anoscopy is important in confirming the presence of a lesion, but only a biopsy can accurately determine the grade of a lesion.

  3. Original Articles

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    2. Original Articles
    3. Original Artcles
    4. Original Articles
    1. Fine-Needle Aspiration

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      Cytologic features and histologic correlations of microacinar and microtrabecular types of well-differentiated hepatocellular carcinoma in fine-needle aspiration biopsy (pages 27–33)

      Grace C. H. Yang, Guang-Yu Yang and Liang-Che Tao

      Version of Record online: 11 DEC 2003 | DOI: 10.1002/cncr.20000

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      Well-differentiated hepatocellular carcinoma in fine-needle aspiration biopsies (FNAs) may present as small hepatocytes with minimal nuclear atypia grouped in microtrabeculae one or more cells thick and microacini of five or more cells without peripheral endothelium. In this study, the cytologic findings in 14 cases with histologic correlations are reported.

    2. Immunocytochemistry

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      Optimal fixation conditions for immunocytochemical analysis of estrogen receptor in cytologic specimens of breast carcinoma (pages 34–40)

      Yun Gong, W. Fraser Symmans, Savitri Krishnamurthy, Shobha Patel and Nour Sneige

      Version of Record online: 9 DEC 2003 | DOI: 10.1002/cncr.11906

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      Antigen retrieval significantly improved immunodetectability of estrogen receptor (ER). Archival Papanicolaou-stained smears were reliably used for retrospective analysis of ER.

    3. Analytical and Quantitative Cytopathology

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      Diagnostic and prognostic use of DNA image cytometry in cervical squamous intraepithelial lesions and invasive carcinoma (pages 41–54)

      Alfred Böcking and Vu Quoc Huy Nguyen

      Version of Record online: 29 DEC 2003 | DOI: 10.1002/cncr.11889

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      Formerly a research tool, standardized DNA image cytometry (DNA-ICM) has become a useful and low-cost laboratory method for establishing objectively and reproducibly an early diagnosis of prospectively progressive cervical intraepithelial lesions at a high-quality level. DNA-ICM may contribute further to the monitoring of treatment for patients with invasive cervical malignancies.

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      Fine-needle cytology and flow cytometry immunophenotyping and subclassification of non-hodgkin lymphoma : A critical review of 307 cases with technical suggestions (pages 55–65)

      Pio Zeppa, Gilda Marino, Giancarlo Troncone, Franco Fulciniti, Amalia De Renzo, Marco Picardi, Giulio Benincasa, Bruno Rotoli, Antonio Vetrani and Lucio Palombini

      Version of Record online: 11 DEC 2003 | DOI: 10.1002/cncr.11903

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      In a critical review of 307 lymph node and extra lymph node lymphoproliferative disorders that were diagnosed with flow cytometry (FC) and fine-needle cytology (FNC), the authors found that FC applied to FNC enhanced the precision of cytologic diagnosis and allowed further subclassification of disorders, thus avoiding invasive surgical biopsies in many patients.

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