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Cancer

Cover image for Cancer

1 August 2005

Volume 104, Issue 3

Pages 443–667

  1. Review Article

    1. Top of page
    2. Review Article
    3. Original Article
    4. Original Articles
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    14. Original Articles
    15. Correspondence
    16. Erratum
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      Clinical management of osteoporosis in women with a history of breast carcinoma (pages 443–456)

      Catherine Van Poznak and Nicholas P. Sauter

      Article first published online: 20 JUN 2005 | DOI: 10.1002/cncr.21201

      Osteoporosis and breast carcinoma are prevalent conditions in American women, and these diseases commonly coexist in the same individuals. In this review, the authors addressed the evaluation and treatment of osteoporosis in women who had a history of early-stage breast carcinoma.

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      Psychologic and social sequelae of secondary lymphedema : A review (pages 457–466)

      Janis McWayne and Sue P. Heiney

      Article first published online: 20 JUN 2005 | DOI: 10.1002/cncr.21195

      The current review article supported the view that secondary lymphedema contributes to psychological and social sequelae after treatment for breast carcinoma. Pain was a significant predictor of psychological and social morbidity.

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      The role of anxiety in prostate carcinoma : A structured review of the literature (pages 467–478)

      William Dale, Pinar Bilir, Misop Han and David Meltzer

      Article first published online: 15 JUN 2005 | DOI: 10.1002/cncr.21198

      Because the data on anxiety levels in patients with prostate carcinoma has been collected piecemeal, using different scales or even unvalidated instruments, the authors conducted a systematic review of the medical literature for high-quality articles that quantified anxiety levels in men with prostate carcinoma.

  2. Original Article

    1. Top of page
    2. Review Article
    3. Original Article
    4. Original Articles
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    14. Original Articles
    15. Correspondence
    16. Erratum
    1. Disease Site

      Breast Disease
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      Predictors of systemic recurrence and disease-specific survival after ipsilateral breast tumor recurrence (pages 479–490)

      Jeannie Shen, Kelly K. Hunt, Nadeem Q. Mirza, Thomas A. Buchholz, Gildy V. Babiera, Henry M. Kuerer, Isabelle Bedrosian, Merrick I. Ross, Frederick C. Ames, Barry W. Feig, S. Eva Singletary, Massimo Cristofanilli and Funda Meric-Bernstam

      Article first published online: 20 JUN 2005 | DOI: 10.1002/cncr.21224

      The management of patients with ipsilateral breast tumor recurrences (IBTR) remains controversial. In this study, the authors found that initial lymph node-positive disease and skin involvement or lymphovascular invasion at IBTR were independent predictors of poor outcome after IBTR.

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      Professional and economic factors affecting access to mammography: A crisis today, or tomorrow? : Results from a national survey (pages 491–498)

      Dione M. Farria, Maria E. Schmidt, Barbara S. Monsees, Robert A. Smith, Charles Hildebolt, Roberta Yoffie, Debra L. Monticciolo, Stephen A. Feig and Lawrence W. Bassett

      Article first published online: 22 JUN 2005 | DOI: 10.1002/cncr.21304

      Objective data and anecdotal reports suggest that mammography access may be declining due to facility closures and difficulty in recruiting and retaining radiologists and radiologic technologists. To gain greater insight into the challenges and concerns of breast imagers, and to establish objective baseline data for the assessment of trends in access to screening, the Society of Breast Imaging conducted a national survey of breast imaging practices in the U.S.

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      The clinical use of staging bone scan in patients with breast carcinoma : Reevaluation by the 2003 American Joint Committee on Cancer staging system (pages 499–503)

      Jeong Eon Lee, Sung-Shin Park, Wonshik Han, Seok Won Kim, Hyuk Jai Shin, Kuk Jin Choe, Seung Keun Oh, Yeo-Kyu Youn, Dong-Young Noh and Sung-Won Kim

      Article first published online: 20 JUN 2005 | DOI: 10.1002/cncr.21200

      The authors evaluated the usefulness of the staging bone scan in patients with primary breast carcinoma in the era of the new 2003 American Joint Committee on Cancer (AJCC) staging system. Stage reclassification resulted in a significant decrease in the bone metastasis rate in patients with Stage IIB breast carcinoma, suggesting that the staging bone scan was of little value for patients with Stage I and II breast carcinoma using the new 2003 AJCC staging system.

  3. Original Articles

    1. Top of page
    2. Review Article
    3. Original Article
    4. Original Articles
    5. Original Article
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    14. Original Articles
    15. Correspondence
    16. Erratum
    1. Disease Site

      Genitourinary Disease
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      Chromosome abnormalities in juxtaglomerular cell tumors (pages 504–510)

      Petter Brandal, Lill-Tove Busund and Sverre Heim

      Article first published online: 20 JUN 2005 | DOI: 10.1002/cncr.21205

      The first juxtaglomerular cell tumor (also known as reninoma) to be karyotyped revealed multiple numerical chromosome abnormalities. Comparing with another such tumor that could not be karyotyped but was evaluated by fluorescence in situ hybridization techniques, gain of chromosome 10 and loss of chromosomes 9, X, and most of chromosome arm 11q came across as common cytogenetic abnormalities in both tumors and might consequently be important pathogenetic events.

  4. Original Article

    1. Top of page
    2. Review Article
    3. Original Article
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    14. Original Articles
    15. Correspondence
    16. Erratum
    1. Disease Site

      Genitourinary Disease
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      Histologic coagulative tumor necrosis as a prognostic indicator of renal cell carcinoma aggressiveness (pages 511–520)

      Shomik Sengupta, Christine M. Lohse, Bradley C. Leibovich, Igor Frank, R. Houston Thompson, W. Scott Webster, Horst Zincke, Michael L. Blute, John C. Cheville and Eugene D. Kwon

      Article first published online: 22 JUN 2005 | DOI: 10.1002/cncr.21206

      Histologic coagulative tumor necrosis is associated with adverse clinical, laboratory, and pathologic features and is independently predictive of reduced cancer-specific survival among patients with clear cell and chromophobe renal cell carcinoma, but it is not predictive among those patients with the papillary subtype.

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      Sperm cryopreservation before cancer chemotherapy helps in the emotional battle against cancer (pages 521–524)

      Kazuo Saito, Kotaro Suzuki, Akira Iwasaki, Yasushi Yumura and Yoshinobu Kubota

      Article first published online: 20 JUN 2005 | DOI: 10.1002/cncr.21185

      Sperm cryopreservation for young patients with cancer before they undergo cancer chemotherapy was found to help in the emotional battle against cancer. However, it did not eliminate their fears of infertility.

  5. Original Articles

    1. Top of page
    2. Review Article
    3. Original Article
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    14. Original Articles
    15. Correspondence
    16. Erratum
    1. Disease Site

      Head and Neck Disease
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      High-dose-rate brachytherapy as part of a multidisciplinary treatment of nasopharyngeal lymphoepithelioma in childhood (pages 525–531)

      Ricardo Akiyoshi Nakamura, Paulo Eduardo Ribeiro dos Santos Novaes, Célia Beatriz Gianotti Antoneli, Ricardo César Fogaroli, Antonio Cássio Assis Pellizzon, Robson Ferrigno, Maria Aparecida Conte Maia, João Victor Salvajoli, Adelino José Pereira and Inês Nobuko Nishimoto

      Article first published online: 28 JUN 2005 | DOI: 10.1002/cncr.21207

      The authors found that high-dose rate brachytherapy was an interesting way to deliver radiation therapy in pediatric patients with nasopharyngeal carcinoma, and it resulted in reduced treatment morbidity.

    2. Hematologic Malignancies
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      Long-term clinical outcome of Helicobacter pylori eradication for gastric mucosa-associated lymphoid tissue lymphoma with a reference to second-line treatment (pages 532–540)

      Shotaro Nakamura, Takayuki Matsumoto, Hiroshi Suekane, Shigeo Nakamura, Hiroshi Matsumoto, Motohiro Esaki, Takashi Yao and Mitsuo Iida

      Article first published online: 3 JUN 2005 | DOI: 10.1002/cncr.21152

      The long-term outcome of Helicobacter pylori eradication therapy was investigated in 96 patients with gastric mucosa-associated lymphoid tissue lymphoma. As a second-line treatment for patients not responding to eradication therapy, oral monochemotherapy and radiotherapy had an equivalent efficacy.

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      2-Chlorodeoxyadenosine and cytarabine combination therapy for idiopathic hypereosinophilic syndrome (pages 541–546)

      Elias Jabbour, Srdan Verstovsek, Francis Giles, Varsha Gandhi, Jorge Cortes, Susan O'Brien, William Plunkett, Guillermo Garcia-Manero, C. Ellen Jackson, Hagop Kantarjian and Michael Andreeff

      Article first published online: 23 JUN 2005 | DOI: 10.1002/cncr.21186

      A combination of 2-chlorodeoxyadenosine and cytosine arabinoside chemotherapy was evaluated in patients with hypereosinophilic syndrome, which is characterized by a sustained overproduction of eosinophils in the bone marrow, eosinophilia, tissue infiltration by eosinophils, and subsequent end-organ damage. The combination was useful provided that consolidation therapy was administered to make it effective in prolonging patient survival.

  6. Original Article

    1. Top of page
    2. Review Article
    3. Original Article
    4. Original Articles
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    15. Correspondence
    16. Erratum
    1. Disease Site

      Hematologic Malignancies
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      Outcome of patients with acute myelogenous leukemia after second salvage therapy (pages 547–554)

      Francis Giles, Susan O'Brien, Jorge Cortes, Srdan Verstovsek, Carlos Bueso-Ramos, Jianqin Shan, Sherry Pierce, Guillermo Garcia-Manero, Michael Keating and Hagop Kantarjian

      Article first published online: 22 JUN 2005 | DOI: 10.1002/cncr.21187

      The authors analyzed the outcome of patients with acute myelogenous leukemia undergoing second salvage therapy, and identified prognostic factors associated with response and survival.

  7. Original Articles

    1. Top of page
    2. Review Article
    3. Original Article
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    14. Original Articles
    15. Correspondence
    16. Erratum
    1. Disease Site

      Hematologic Malignancies
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      Hyperfractionated cyclophosphamide with high-doses of arabinosylcytosine and methotrexate (HyperCHiDAM Verona 897) : An intensive and effective regimen for patients with aggressive, refractory or recurrent non-Hodgkin lymphomas after anthracycline-containing regimens (pages 555–560)

      Giuseppe Todeschini, Cristina Tecchio, Felice Pasini, Fabio Benedetti, Maurizio Cantini, Claudia Crippa, Michela Draisci and Giovanni Pizzolo

      Article first published online: 15 JUN 2005 | DOI: 10.1002/cncr.21150

      An intensive regimen that included high-dose methotrexate, high-dose arabinosylcytosine, and hyperfractionated cyclophosphamide was employed to induce complete remission in 28 consecutive patients who had aggressive non-Hodgkin lymphomas that were refractory or that recurred after anthracycline-containing regimens. This protocol allowed the achievement of a complete remission rate of 64.3% and the harvest of CD34-positive cells for a subsequent stem cell transplantation. At the time of this report, 13 of 28 patients (46.42%) were event-free. The median follow-up for all patients was 35 months (range, from 2 months to ≥ 74 months).

  8. Original Article

    1. Top of page
    2. Review Article
    3. Original Article
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    15. Correspondence
    16. Erratum
    1. Disease Site

      Lung Disease
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      Phase II study of the farnesyltransferase inhibitor lonafarnib with paclitaxel in patients with taxane-refractory/resistant nonsmall cell lung carcinoma (pages 561–569)

      Edward S. Kim, Merrill S. Kies, Frank V. Fossella, Bonnie S. Glisson, Sara Zaknoen, Paul Statkevich, Reginald F. Munden, Carmen Summey, Katherine M.W. Pisters, Vali Papadimitrakopoulou, Mourad Tighiouart, Andre Rogatko and Fadlo R. Khuri

      Article first published online: 18 JUL 2005 | DOI: 10.1002/cncr.21188

      Lonafarnib plus paclitaxel demonstrated clinical activity in patients with taxane-refractory/resistant metastatic nonsmall cell lung carcinoma. In addition, the combination of lonafarnib and paclitaxel was well tolerated with minimal toxicity. Evaluation of this combination therapy in additional clinical trials is warranted.

  9. Original Articles

    1. Top of page
    2. Review Article
    3. Original Article
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    14. Original Articles
    15. Correspondence
    16. Erratum
    1. Disease Site

      Melanoma
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      Inefficacy of F-18 fluorodeoxy-D-glucose-positron emission tomography scans for initial evaluation in early-stage cutaneous melanoma (pages 570–579)

      Jeffrey D. Wagner, Donald Schauwecker, Darrell Davidson, Theodore Logan, John J. Coleman III, Gary Hutchins, Charlene Love, Stacie Wenck and Joanne Daggy

      Article first published online: 23 JUN 2005 | DOI: 10.1002/cncr.21189

      F-18 fluorodeoxy-D-glucose positron emission tomography (FDG-PET) scanning in patients with early-stage melanoma at the time of presentation was an insensitive indicator of occult melanoma lymph node metastases compared with sentinel lymph node biopsy and was no more useful than conventional staging for detection of occult Stage IV disease. FDG-PET should not be used routinely for initial metastatic evaluation in patients with early-stage melanoma.

    2. Neuro-Oncology
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      Hearing preservation after gamma knife stereotactic radiosurgery of vestibular schwannoma (pages 580–590)

      Sun Ha Paek, Hyun-Tai Chung, Sang Soon Jeong, Chul-Kee Park, Chae-Yong Kim, Jeong Eun Kim, Dong Gyu Kim and Hee-Won Jung

      Article first published online: 10 JUN 2005 | DOI: 10.1002/cncr.21190

      Using a prospective study design, the authors evaluated the hearing preservation rate and determined its prognostic factors after gamma knife (GK) stereotactic radiosurgery (SRS) in a series of patients with vestibular schwannoma. The results indicated that a more sophisticated strategy to prevent hearing deterioration during the first 6 months post-GK SRS is necessary to improve long-term hearing preservation.

  10. Original Article

    1. Top of page
    2. Review Article
    3. Original Article
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    15. Correspondence
    16. Erratum
    1. Disease Site

      Neuro-Oncology
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      Analysis of clonal immunoglobulin heavy chain rearrangements in ocular lymphoma (pages 591–597)

      Joachim M. Baehring, Sofia Androudi, Janina J. Longtine, Rebecca A. Betensky, Jeffrey Sklar, C. Stephen Foster and Fred H. Hochberg

      Article first published online: 22 JUN 2005 | DOI: 10.1002/cncr.21191

      Morphologic diagnosis of intraocular lymphoma (IOL) is often difficult because of low cellularity and the fragility of lymphocytes in vitreous biopsy specimens. In the current study, analysis of immunoglobulin heavy chain gene rearrangements was a useful method to improve diagnostic accuracy and the combined use of this modality with cytopathology and flow cytometry substantially increased the diagnostic yield in IOL.

  11. Original Articles

    1. Top of page
    2. Review Article
    3. Original Article
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    15. Correspondence
    16. Erratum
    1. Disease Site

      Neuro-Oncology
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      Proliferation and progesterone receptor status in benign meningiomas are not age dependent (pages 598–601)

      Florian Roser, Makoto Nakamura, Rainer Ritz, Mattia Bellinzona, Klaus Dietz, Madjid Samii and Marcos S. Tatagiba

      Article first published online: 10 JUN 2005 | DOI: 10.1002/cncr.21192

      In the current study, meningiomas in elderly patients were found to exhibit histology and proliferation rates similar to those in younger patients. Therefore, the therapeutic strategy should be determined independent of the patient's age.

    2. Sarcoma
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      Infections in children and young adults with bone malignancies undergoing limb-sparing surgery (pages 602–610)

      Aditya H. Gaur, Tiebin Liu, Katherine M. Knapp, Najat C. Daw, Bhaskar N. Rao, Michael D. Neel, Carlos Rodriguez-Galindo, Diane Brand and Elisabeth E. Adderson

      Article first published online: 10 JUN 2005 | DOI: 10.1002/cncr.21212

      Current treatment for bone malignancies is complicated by an unexpectedly high incidence of infection. Orthopedic device infections occurred in 21% of patients, and children and young adults with these infections had an increased risk of both poor functional outcomes and amputation despite early and prolonged antimicrobial therapy.

  12. Original Article

    1. Top of page
    2. Review Article
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    15. Correspondence
    16. Erratum
    1. Disease Site

      Sarcoma
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      Ifosfamide/liposomal daunorubicin is a well tolerated and active first-line chemotherapy regimen in advanced soft tissue sarcoma : Results of a Phase II study (pages 611–617)

      Jan M. Siehl, Eckhard Thiel, Alexander Schmittel, Gero Hütter, Peter M. Deckert, Hubert Szelényi and Ulrich Keilholz

      Article first published online: 20 JUN 2005 | DOI: 10.1002/cncr.21211

      The combination of a moderate dose of continuous infusion ifosfamide with liposomal daunorubicin was found to be a highly active and well tolerated chemotherapy regimen for first-line treatment of soft tissue sarcoma.

    2. Discipline

      Epidemiology
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      Epidemiology and outcomes of serious influenza-related infections in the cancer population (pages 618–628)

      Catherine D. Cooksley, Elenir B. C. Avritscher, Benjamin N. Bekele, Kenneth V. Rolston, Jane M. Geraci and Linda S. Elting

      Article first published online: 22 JUN 2005 | DOI: 10.1002/cncr.21203

      Death from influenza-related infections was reported to occur in an estimated 9% of patients with cancer who were hospitalized for influenza. Using recommended vaccination schedules for patients with cancer and their contacts reduced hospitalizations, treatment delays, and deaths in this highly susceptible population.

  13. Original Articles

    1. Top of page
    2. Review Article
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    15. Correspondence
    16. Erratum
    1. Discipline

      Epidemiology
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      Differences in colorectal carcinoma stage and survival by race and ethnicity (pages 629–639)

      Chloe Chien, Libby M. Morimoto, Jamie Tom and Christopher I. Li

      Article first published online: 27 JUN 2005 | DOI: 10.1002/cncr.21204

      Among patients with colorectal carcinoma, numerous disparities in the risks of advanced-stage cancer and mortality were observed by race/ethnicity. There was also considerable variation in these risks across Asian/Pacific Islander and Hispanic white subgroups.

    2. Medical Oncology
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      Successful carboplatin desensitization in patients with proven carboplatin allergy (pages 640–643)

      Ronit Confino-Cohen, Amiram Fishman, Marco Altaras and Arnon Goldberg

      Article first published online: 23 JUN 2005 | DOI: 10.1002/cncr.21168

      The data presented a successful desensitization protocol for individuals with a proven allergic reaction to carboplatin. The protocol was safe and convenient, and offered an effective therapeutic strategy to patients who required this drug.

    3. Pediatric Oncology
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      Percutaneous biopsy of pediatric solid tumors (pages 644–652)

      Kevin M. Garrett, Christine E. Fuller, Victor M. Santana, Stephen J. Shochat and Fredric A. Hoffer

      Article first published online: 28 JUN 2005 | DOI: 10.1002/cncr.21193

      The authors conducted a retrospective review of clinical data related to 202 imaging-guided percutaneous biopsies of pediatric solid tumor malignancies. By using this technique, radiologists obtained an overall diagnostic accuracy of 93%.

    4. Psychological Oncology
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      Sociodemographic determinants of cancer treatment health literacy (pages 653–660)

      Ted Gansler, S. Jane Henley, Kevin Stein, Eric J. Nehl, Carol Smigal and Edwin Slaughter

      Article first published online: 27 JUN 2005 | DOI: 10.1002/cncr.21194

      A telephone survey of adult U.S. residents revealed a high prevalence of several misconceptions regarding treatment. There were substantial socioeconomic differences in the prevalence of these misconceptions, which may be a factor contributing to disparities in cancer outcomes.

  14. Correspondence

    1. Top of page
    2. Review Article
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    15. Correspondence
    16. Erratum
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      Author reply (pages 662–663)

      Beth A. Jones, Stanislav V. Kasl and Robert Dubrow

      Article first published online: 25 MAY 2005 | DOI: 10.1002/cncr.21213

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      Author reply (pages 663–664)

      Gábor Cserni

      Article first published online: 23 JUN 2005 | DOI: 10.1002/cncr.21197

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      Author reply (pages 665–666)

      James A. Welker

      Article first published online: 22 JUN 2005 | DOI: 10.1002/cncr.21208

  15. Erratum

    1. Top of page
    2. Review Article
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    15. Correspondence
    16. Erratum
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