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Cancer Cytopathology

Cover image for Cancer Cytopathology

25 February 2005

Volume 105, Issue 1

Pages 1–51

Currently known as: Cancer Cytopathology

  1. Editorial

    1. Top of page
    2. Editorial
    3. Original Articles
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      A new collaboration (page 1)

      William J. Frable

      Article first published online: 13 DEC 2004 | DOI: 10.1002/cncr.20833

  2. Original Articles

    1. Top of page
    2. Editorial
    3. Original Articles
    1. Gynecologic Cytopathology

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      Triage with human papillomavirus testing of women with cytologic abnormalities prompting referral for colposcopy assessment (pages 2–7)

      Francesca Maria Carozzi, Massimo Confortini, Silvia Cecchini, Simonetta Bisanzi, Maria Paola Cariaggi, Giovanni Pontenani, Maria Rosaria Raspollini, Cristina Sani, Marco Zappa and Stefano Ciatto

      Article first published online: 8 DEC 2004 | DOI: 10.1002/cncr.20736

      The current study was based on a relatively large, unbiased colposcopy series and a retrospective cost-effectiveness analysis of the impact of human papillomavirus (HPV) triage based on a number of considerations. The sensitivity of HPV testing for cervical intraepithelial neoplasia > Grade 2 was very high, and cost analysis indicated a moderate increase in cost with the addition of HPV triage. Because it is highly sensitivity, HPV testing may be useful as an alternative to the current policy of 6-month repeat cytology for women who have atypical squamous cells of undetermined significance.

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      Cytologic scoring of endometrioid adenocarcinoma of the endometrium : Correlation with histologic grade and clinicopathologic factors (pages 8–12)

      Yukari Nishimura, Jun Watanabe, Toshiko Jobo, Manabu Hattori, Tsutomu Arai and Hiroyuki Kuramoto

      Article first published online: 13 DEC 2004 | DOI: 10.1002/cncr.20787

      A cytologic scoring system for endometrioid adenocarcinoma proved useful for predicting histologic grade and tumor malignant potential.

    3. Non-Gynecologic Cytopathology

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      Accuracy of intraoperative imprint cytology for sentinel lymph node evaluation in the treatment of breast carcinoma : A 6-year study (pages 13–20)

      Charles Cox, Barbara Centeno, Dan Dickson, John Clark, Santo Nicosia, Elisabeth Dupont, Harvey Greenberg, Nicholas Stowell, Laura White, Jayesh Patel, Ben Furman, Alan Cantor, Ardeshir Hakam, Nazeel Ahmad, Nils Diaz and Jeff King

      Article first published online: 16 DEC 2004 | DOI: 10.1002/cncr.20738

      The authors report results from a large retrospective analysis of intraoperative imprint cytology performed on axillary sentinel lymph nodes (IICN) removed over the course of 2137 breast surgeries. IICN was found to accurately predict final lymph node status in 85.0% of patients. Although the accuracy of this technique varies with tumor size and type, the authors conclude that IICN is an accurate, practical, morbidity-reducing, and cost-effective procedure.

    4. Fine-Needle Aspiration

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      Cytologic features of ductal carcinoma in situ in fine-needle aspiration of the breast mirror the histopathologic growth pattern heterogeneity and grading (pages 21–27)

      Torill Sauer, Jon Lømo, Øystein Garred and Oddvar Næss

      Article first published online: 8 DEC 2004 | DOI: 10.1002/cncr.20735

      The findings in fine-needle aspiration cytology samples from ductal carcinoma in situ of the breast completely mirror the histologic heterogeneity of growth pattern subtypes. To the authors' knowledge, pure subtypes are virtually nonexistent. Primary cytologic grading can effectively distinguish the high-grade lesions from the nonhigh-grade lesions.

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      Cytologic features of renal medullary carcinoma : A study of three cases (pages 28–34)

      Lina Assad, Erika Resetkova, Victor L. Oliveira, Wei Sun, John M. Stewart, Ruth L. Katz and Nancy P. Caraway

      Article first published online: 8 DEC 2004 | DOI: 10.1002/cncr.20764

      Renal medullary carcinoma is rare and occurs primarily in young black men with sickle cell disease or trait. It is highly aggressive and is associated with a poor prognosis, even with therapy. The authors discuss the cytologic features of three cases and the differential diagnosis of this rare disease.

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      Comparison of molecular abnormalities in bronchial brushings and tumor touch preparations : Potential use of fluorescence in situ hybridization to identify predictive markers in early-stage lung carcinomas (pages 35–43)

      Güliz A. Barkan, Nancy P. Caraway, Feng Jiang, Tanweer M. Zaidi, Ricardo Fernandez, Ara Vaporcyin, Rodolfo Morice, Xian Zhou, Benjamin Nebiyou Bekele and Ruth L. Katz

      Article first published online: 16 DEC 2004 | DOI: 10.1002/cncr.20800

      The authors compared molecular abnormalities in cytologically normal bronchial epithelial cells and tumor touch imprints from patients with known early-stage nonsmall cell lung carcinomas. They used fluorescence in situ hybridization analysis with two probes developed in-house and a commercially available multicolor probe.

    7. Analytical and Quantitative Cytopathology

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      Cytologic factors associated with prognosis in patients with peripheral adenocarcinoma of the lung measuring 3 cm or less in greatest dimension (pages 44–51)

      Yukihiro Kobayashi, Tomoyuki Yokose, Kimihiko Kawamura, Seiji Iwasaki, Yukinori Murata, Shinkichi Onuma, Takahiro Hasebe, Kanji Nagai, Satoshi Sasaki and Atsushi Ochiai

      Article first published online: 4 NOV 2004 | DOI: 10.1002/cncr.20686

      A small cluster size, multinucleated cells, and nuclear irregularity were independent prognostic factors in patients with peripheral lung adenocarcinomas that measured ≤ 3 cm in greatest dimension.

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