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Cancer Cytopathology

Cover image for Cancer Cytopathology

25 December 2008

Volume 114, Issue 6

Pages 463–528

Currently known as: Cancer Cytopathology

  1. Commentary

    1. Top of page
    2. Commentary
    3. Original Articles
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      The case for pathologist ultrasound-guided fine-needle aspiration biopsy (pages 463–468)

      John S. Abele

      Version of Record online: 27 OCT 2008 | DOI: 10.1002/cncr.23950

      The addition of ultrasound guidance to the pathologist's fine-needle aspiration biopsy armamentarium can improve sampling and patient care, not only for biopsies of the thyroid, but at other tumor sites as well. Good ultrasound-guided biopsy skills are no more difficult to learn than good smear-making skills.

  2. Original Articles

    1. Top of page
    2. Commentary
    3. Original Articles
    1. Gynecologic Cytopathology

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      Pathology correlates of a Papanicolaou diagnosis of low-grade squamous intraepithelial lesion, cannot exclude high-grade squamous intraepithelial lesion (pages 469–473)

      Omar Al-Nourhji, Michael J. Beckmann, Stephen J. Markwell and L. Stewart Massad

      Version of Record online: 5 NOV 2008 | DOI: 10.1002/cncr.23984

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      A diagnosis of low-grade squamous intraepithelial lesion, cannot exclude high-grade squamous intraepithelial lesion (LSIL-H) distinguished women who needed colposcopy from those with LSIL who could be followed cytologically.

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      Comparison of ProEx C with p16INK4a and Ki-67 immunohistochemical staining of cell blocks prepared from residual liquid-based cervicovaginal material : A pilot study (pages 474–480)

      Ruba A. Halloush, Ilkser Akpolat, Qihui “Jim” Zhai, Mary R. Schwartz and Dina R. Mody

      Version of Record online: 17 NOV 2008 | DOI: 10.1002/cncr.23951

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      Cell blocks can be prepared from residual liquid-based cervicovaginal material and used for immunohistochemistry. ProEx C is a nuclear stain, and is cleaner and easier to interpret compared with p16, even in scant specimens.

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      Atypical squamous cells, cannot exclude a high-grade intraepithelial lesion and its clinical significance in postmenopausal, pregnant, postpartum, and contraceptive-use patients (pages 481–488)

      Amber L. Patton, Lisa Duncan, Leneord Bloom, Geneen Phaneuf and Nadeem Zafar

      Version of Record online: 3 NOV 2008 | DOI: 10.1002/cncr.23949

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      Previous studies have confirmed the low predictive value of the diagnosis atypical squamous cells, cannot exclude a high-grade squamous intraepithelial lesion (ASC-H) in Papanicolaou (Pap) tests from postmenopausal women. The objective of the current study was to evaluate the predictive value of ASC-H for subsequent high-grade dysplasia (HSIL) in postmenopausal women compared with other states that result in hormonal alterations, including pregnancy, postpartum, and contraceptive-use patients. The results confirmed that the diagnosis of ASC-H in postmenopausal Pap tests has a low predictive value in the subsequent diagnosis of HSIL, which was in stark contrast to the pregnant, postpartum, and contraceptive-use categories, indicating that age rather than hormonal alterations affect the capacity of ASC-H to predict subsequent HSIL.

    4. Non-Gynecologic Cytopathology

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      Detection of human papillomavirus infection in penile samples through liquid-based cytology and polymerase chain reaction (pages 489–493)

      Maria Gabrielle de Lima Rocha, Fábio Lopes Faria, Maria do Carmo M. Souza, Annamaria Ravara Vago, Ana Paula Fernandes and Paula Ávila Fernandes

      Version of Record online: 30 OCT 2008 | DOI: 10.1002/cncr.23947

      The cytopathologic detection of human papillomavirus (HPV) infection in penile samples collected for liquid-based cytology is low and does not appear to improve the diagnosis of HPV infection in men.

    5. Fine-Needle Aspiration

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      Comparative evaluation of flow-cytometric immunophenotyping and immunocytochemistry in the categorization of malignant small round cell tumors in fine-needle aspiration cytologic specimens (pages 494–503)

      Upasana Gautam, Radhika Srinivasan, Arvind Rajwanshi, Deepak Bansal and Ram Kumar Marwaha

      Version of Record online: 15 DEC 2008 | DOI: 10.1002/cncr.23948

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      Flow-cytometric immunophenotyping complemented immunocytochemistry for the accurate typing of malignant small round cell tumors in material obtained by fine-needle aspiration.

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      Cytologic features of extragonadal germ cell tumors : A study of 88 cases with aspiration cytology (pages 504–511)

      Ruchika Gupta, Sandeep R. Mathur, Vinod K. Arora and Shree G. Sharma

      Version of Record online: 3 NOV 2008 | DOI: 10.1002/cncr.23983

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      The authors evaluated the cytologic features of primary extragonadal germ cell tumors (GCTs) and their metastasis from gonadal sites in fine-needle aspiration (FNA) cytology. The results indicated that FNA cytology reliably offers a diagnosis of GCT at extragonadal sites, even in rare locations and in patients who have metastatic tumor as their first clinical presentation.

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      Thin core needle biopsy crush preparations in conjunction with fine-needle aspiration for the evaluation of thyroid nodules : A complementary approach (pages 512–518)

      Songlin Zhang, Marina Ivanovic, Albert A. Nemcek Jr., Denise V. S. DeFrias, Erin Lucas and Ritu Nayar

      Version of Record online: 5 NOV 2008 | DOI: 10.1002/cncr.23982

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      Fine-needle aspiration (FNA) is widely accepted as the initial test to evaluate thyroid nodules. However, its limitations have included inadequate and suboptimal specimens. The results from the current study indicated that FNA in conjunction with a thin core needle biopsy/crush preparation performed during the same procedure is a safe technique that can reduce the rate of unsatisfactory and suboptimal thyroid biopsies.

    8. Immunocytochemistry

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      Placental isoform glutathione S-transferase and P-glycoprotein expression in advanced nonsmall cell lung cancer : Association with response to treatment and survival (pages 519–526)

      George S. Vlachogeorgos, Effrosini D. Manali, Ekaterini Blana, Stella Legaki, Napoleon Karagiannidis, Vlassios S. Polychronopoulos and Charis Roussos

      Version of Record online: 11 NOV 2008 | DOI: 10.1002/cncr.23981

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      The current results suggested that the easily studied expression of glutathione S-transferase placental isoform and P-glycoprotein in cytology specimens obtained by minimally invasive bronchoscopy may serve as simple prognostic indicators of response to therapy and survival in patients with advanced nonsmall cell lung cancer.

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