Is sex associated with the outcome of patients treated with radiation for nonsmall cell lung cancer? (pages 3233–3242)
Susan L. McGovern, Zhongxing Liao, M. Kara Bucci, Mary Frances McAleer, Melenda D. Jeter, Joe Y. Chang, Michael S. O'Reilly, James D. Cox, Pamela K. Allen and Ritsuko Komaki
Article first published online: 26 MAY 2009 | DOI: 10.1002/cncr.24361
A retrospective review of 831 nonsmall cell lung cancer (NSCLC) patients treated with radiation revealed that despite equivalent treatment, women with medically inoperable stage I disease have improved overall survival compared with men. Along with known prognostic factors for NSCLC, such as age, weight loss, and stage, sex remained significant on multivariate analysis of overall survival, supporting the hypothesis that sex is an important determinant of outcome in NSCLC patients receiving radiation.