You have free access to this content

Cancer

Cover image for Cancer

1 May 2009

Volume 115, Issue 9

Pages 1805–2024

  1. News

    1. Top of page
    2. News
    3. Editorial
    4. Review Articles
    5. Original Articles
    6. Errata
    1. You have free access to this content
      CancerScope (pages 1805–1807)

      Carrie Printz

      Article first published online: 20 APR 2009 | DOI: 10.1002/cncr.24318

  2. Editorial

    1. Top of page
    2. News
    3. Editorial
    4. Review Articles
    5. Original Articles
    6. Errata
    1. You have free access to this content
      Stigma associated with “palliative care” : Getting around it or getting over it (pages 1808–1812)

      Nathan I. Cherny

      Article first published online: 20 FEB 2009 | DOI: 10.1002/cncr.24212

      Palliative care and the stigma associated with its name are discussed.

  3. Review Articles

    1. Top of page
    2. News
    3. Editorial
    4. Review Articles
    5. Original Articles
    6. Errata
    1. You have free access to this content
      A woman's heart : The impact of adjuvant endocrine therapy on cardiovascular health (pages 1813–1826)

      Michael S. Ewer and Stefan Glück

      Article first published online: 20 FEB 2009 | DOI: 10.1002/cncr.24219

      The results from this review indicated that adjuvant therapy in postmenopausal woman with breast cancer may contribute to the expression of underlying cardiovascular disease or expose the heart to additional toxicities. Because women live longer after being diagnosed with breast cancer, the potential impact of adjuvant therapies on cardiovascular risk becomes an important consideration for clinicians.

    2. You have free access to this content
      Late rectal complications after prostate brachytherapy for localized prostate cancer : Incidence and management (pages 1827–1839)

      Jack Phan, David A. Swanson, Lawrence B. Levy, Rajat J. Kudchadker, Teresa L. Bruno and Steven J. Frank

      Article first published online: 26 FEB 2009 | DOI: 10.1002/cncr.24223

      The authors reviewed the clinical manifestations, incidence, and treatment of late rectal complications after prostate brachytherapy. The results indicated that many patients who undergo prostate brachytherapy rely on their primary care physician, gastroenterologist, or colorectal surgeon for the management of late rectal complications after brachytherapy. The information provided in this article should help such clinicians provide patients with appropriate supportive care.

  4. Original Articles

    1. Top of page
    2. News
    3. Editorial
    4. Review Articles
    5. Original Articles
    6. Errata
    1. Disease Site

      Gastrointestinal Disease
      You have free access to this content
      Identification of 12 or more lymph nodes in resected colon cancer specimens as an indicator of quality performance (pages 1840–1848)

      Robert O. Dillman, Kenneth Aaron, F. Scott Heinemann and Stephanie E. McClure

      Article first published online: 10 FEB 2009 | DOI: 10.1002/cncr.24185

      Identification of 12 or more lymph nodes was a predictor of survival in patients undergoing resection of colon cancer. Variables associated with the probability of identifying 12 or more lymph nodes included anatomic location, training in colorectal surgery, colon cancer case volume, patient age, and disease stage.

    2. You have free access to this content
      Radioembolization of colorectal hepatic metastases using yttrium-90 microspheres (pages 1849–1858)

      Mary F. Mulcahy, Robert J. Lewandowski, Saad M. Ibrahim, Kent T. Sato, Robert K. Ryu, Bassel Atassi, Steven Newman, Mark Talamonti, Reed A. Omary, Al Benson III and Riad Salem

      Article first published online: 6 MAR 2009 | DOI: 10.1002/cncr.24224

      The objective of the current study was to determine the safety and efficacy of Yttrium-90 (Y90) microsphere treatment in patients with liver-dominant colorectal metastases. The results indicated that Y90 liver therapy provided sustained disease stabilization with acceptable toxicity, and asymptomatic patients who had preserved liver function at the time of Y90 treatment appeared to benefit most.

    3. Genitourinary Disease
      You have free access to this content
      Patterns of disease progression in metastatic renal cell carcinoma patients treated with antivascular agents and interferon : Impact of therapy on recurrence patterns and outcome measures (pages 1859–1866)

      Elizabeth R. Plimack, Nizar Tannir, E Lin, B. Nebiyou Bekele and Eric Jonasch

      Article first published online: 24 FEB 2009 | DOI: 10.1002/cncr.24211

      Differences in patterns of progression between patients treated with antivascular agents or interferon, and the impact of disease stabilization on outcome, were investigated. Antivascular therapy may be more effective at controlling existing sites of disease than it is at preventing new metastases.

    4. Gynecologic Oncology
      You have free access to this content
      Phase 2 trial of mifepristone (RU-486) in advanced or recurrent endometrioid adenocarcinoma or low-grade endometrial stromal sarcoma (pages 1867–1874)

      Lois M. Ramondetta, Alaina J. Johnson, Charlotte C. Sun, Neely Atkinson, Judith A. Smith, Maria S. Jung, Russel Broaddus, Revathy B. Iyer and Thomas Burke

      Article first published online: 24 FEB 2009 | DOI: 10.1002/cncr.24197

      The objective of this study was to determine the efficacy of mifepristone (RU-486) in women with advanced or recurrent endometrioid adenocarcinoma or low-grade endometrial stromal sarcoma. Mifepristone produced stable disease in patients with endometrial cancer, but it resulted in no partial or complete responses.

    5. You have free access to this content
      Prognostic impact of mitotic index of proliferating cell populations in cervical cancer patients treated with carbon ion beam (pages 1875–1882)

      Yoshiyuki Suzuki, Kuniyuki Oka, Tatsuya Ohno, Shingo Kato, Hirohiko Tsujii and Takashi Nakano

      Article first published online: 17 FEB 2009 | DOI: 10.1002/cncr.24189

      High mitotic index of a proliferating cell population was found to be an indication of a poorer prognosis, and was a powerful prognostic factor in patients with squamous cell carcinomas of the cervix treated with carbon ion beam therapy.

    6. Head and Neck Disease
      You have free access to this content
      Metastatic cutaneous squamous cell carcinoma of the head and neck : The Immunosuppression, Treatment, Extranodal spread, and Margin status (ITEM) prognostic score to predict outcome and the need to improve survival (pages 1883–1891)

      Nicolas Oddone, Gary J. Morgan, Carsten E. Palme, Lakmalie Perera, Jennifer Shannon, Eva Wong, Val Gebski and Michael J. Veness

      Article first published online: 17 FEB 2009 | DOI: 10.1002/cncr.24208

      The authors developed a prognostic score model using a prospective study of patients who had regional, metastatic, cutaneous squamous cell carcinoma of the head and neck. The results indicated that the patients who had moderate or high-risk scores, usually because of extranodal spread and involved excision margins, had a poor outcome, and the authors recommend considering these patients for inclusion in trials of adjuvant chemoradiotherapy.

    7. Hematologic Malignancies
      You have free access to this content
      Efficacy and safety of liposomal cytarabine in lymphoma patients with central nervous system involvement from lymphoma (pages 1892–1898)

      Jose A. Garcia-Marco, Carlos Panizo, Eva Sanchez Garcia, Guillermo Deben, Alberto Alvarez-Larran, Eva Gonzalez Barca, Juan Manuel Sancho, Maria Jesus Penarrubia, Tomas Garcia-Cerecedo and Jose A. García-Vela

      Article first published online: 20 FEB 2009 | DOI: 10.1002/cncr.24204

      Liposomal cytarabine (DepoCyte) was used to treat lymphomatous meningitis in a series of 55 patients with lymphoma in Spain. Treatment was associated with a neurologic response rate of 72% and a median time to neurologic progression of 105.5 days.

    8. You have free access to this content
      Low-dose azacitidine after allogeneic stem cell transplantation for acute leukemia (pages 1899–1905)

      Elias Jabbour, Sergio Giralt, Hagop Kantarjian, Guillermo Garcia-Manero, Madan Jagasia, Partow Kebriaei, Leandro de Padua, Elizabeth J. Shpall, Richard Champlin and Marcos de Lima

      Article first published online: 20 FEB 2009 | DOI: 10.1002/cncr.24198

      The authors hypothesized that low doses of the hypomethylating agent 5-azacitidine may maximize the graft-versus-leukemia effect and may be tolerated well after stem cell transplantation in patients with acute leukemia. The trial of this low-dose strategy revealed that the drug was safe administered at low doses, there was no exacerbation of graft-versus-host disease, and responses were observed among patients with recurrent disease after 1 or 2 stem cell transplantations.

    9. You have free access to this content
      Anthracycline-fludarabine-containing regimens with or without rituximab in the treatment of patients with advanced follicular lymphoma (pages 1906–1913)

      Stefano Luminari, Luigi Marcheselli, Stefano Sacchi, Samantha Pozzi, Alessia Bari, Fiorella Ilariucci, Caterina Stelitano, Francesco Angrilli, Antonio Lazzaro and Luca Baldini

      Article first published online: 26 FEB 2009 | DOI: 10.1002/cncr.24222

      Recent experience has suggested a stepwise improvement in the survival outcomes of patients who have lymphoma with the introduction of new treatment options. The results from this trial confirmed that the addition of rituximab to anthracycline-fludarabine–containing regimens had a favorable effect on the prognosis of patients with advanced follicular lymphoma.

    10. Hepatobiliary Disease
      You have free access to this content
      Percutaneous thermal ablation of medium and large hepatocellular carcinoma : Long-term outcome and prognostic factors (pages 1914–1923)

      Xiao-Yu Yin, Xiao-Yan Xie, Ming-De Lu, Hui-Xiong Xu, Zuo-Feng Xu, Ming Kuang, Guang-Jian Liu, Jin-Yu Liang and Wan Yee Lau

      Article first published online: 24 FEB 2009 | DOI: 10.1002/cncr.24196

      Percutaneous thermal ablation was effective and safe in treating hepatocelluar carcinoma between 3 and 7 cm, with acceptable local tumor control and long-term outcomes. Completeness of ablation, previous history of treatment, and preablation α-fetoprotein level were found to be significant prognostic factors.

    11. Lung Disease
      You have free access to this content
      Gemcitabine-based doublets versus single-agent therapy for elderly patients with advanced nonsmall cell lung cancer : A Literature-based Meta-analysis (pages 1924–1931)

      Antonio Russo, Sergio Rizzo, Fabio Fulfaro, Vincenzo Adamo, Daniele Santini, Bruno Vincenzi, Nicola Gebbia and Ignazio Carreca

      Article first published online: 20 FEB 2009 | DOI: 10.1002/cncr.24207

      The authors performed a literature-based meta-analysis to assess the efficacy and tolerability of gemcitabine-based doublets compared with single-agent chemotherapy for elderly patients with nonsmall cell lung cancer (NSCLC). The doublets appeared to be effective and feasible compared with single agents in the treatment of elderly patients with advanced NSCLC who were not suitable for full-dose, platinum-based chemotherapy.

    12. Melanoma
      You have free access to this content
      Efficacy of repeat isolated limb infusion with melphalan and actinomycin D for recurrent melanoma (pages 1932–1940)

      Hidde M. Kroon, D-Yin Lin, Peter C. A. Kam and John F. Thompson

      Article first published online: 13 MAR 2009 | DOI: 10.1002/cncr.24220

      Repeat isolated limb infusion (ILI) is an attractive treatment option to achieve limb salvage in patients with inoperable recurrent or progressive melanoma after a previous ILI. It can be associated with significant short-term regional toxicity, but is well tolerated by most patients, with satisfactory response rates.

    13. Neuro-Oncology
      You have free access to this content
      Neoplastic meningitis : Survival as a function of cerebrospinal fluid cytology (pages 1941–1946)

      Marc C. Chamberlain and Sandra K. Johnston

      Article first published online: 23 FEB 2009 | DOI: 10.1002/cncr.24210

      Patients with neoplastic meningitis not infrequently demonstrated negative cerebrospinal fluid (CSF) cytology. In comparing matched (histology, age, performance status, etcn) patients with and without positive CSF cytology, survival was similar, suggesting that CSF negativity does not predict outcome.

    14. You have free access to this content
      Intracranial dural metastases (pages 1947–1953)

      Lakshmi Nayak, Lauren E. Abrey and Fabio M. Iwamoto

      Article first published online: 24 FEB 2009 | DOI: 10.1002/cncr.24203

      The authors retrospectively reviewed 122 patients with intracranial dural metastases (IDM) and most common primary tumors were breast, prostate, and lung cancer. Most IDM patients had active systemic cancer; poor performance status and lung cancer were associated with worse survival.

    15. Discipline

      Epidemiology
      You have free access to this content
      Breast cancer survivors in the United States : Geographic Variability and Time Trends, 2005-2015 (pages 1954–1966)

      Roberta De Angelis, Andrea Tavilla, Arduino Verdecchia, Steve Scoppa, Mark Hachey, Eric J. Feuer and Angela B. Mariotto

      Article first published online: 26 FEB 2009 | DOI: 10.1002/cncr.24217

      In this study, the authors provide the first systematic estimation of breast cancer prevalence in all US states up to the year 2015. The estimated levels and time trends were consistent with the available population-based data on breast cancer incidence, prevalence, and population aging.

    16. You have free access to this content
      Colorectal cancer incidence in the United States, 1999-2004 : An updated analysis of data from the National Program of Cancer Registries and the Surveillance, Epidemiology, and End Results Program (pages 1967–1976)

      Sun Hee Rim, Laura Seeff, Faruque Ahmed, Jessica B. King and Steven S. Coughlin

      Article first published online: 20 FEB 2009 | DOI: 10.1002/cncr.24216

      Colorectal cancer (CRC) screening guidelines have not been based on disease burden by demographic subpopulations until recently. By using updated national cancer surveillance data, the authors investigated CRC incidence by subpopulation, and the results provided information that may be useful in formulating strategies to reduce CRC incidence.

    17. Pathology
      You have free access to this content
      Central pathology review in multicenter trials and studies : Lessons from the nephroblastoma trials (pages 1977–1983)

      Gordan M. Vujanić, Bengt Sandstedt, Anna Kelsey and Neil J. Sebire

      Article first published online: 24 FEB 2009 | DOI: 10.1002/cncr.24214

      The number and quality of material submitted for central pathology review (CPR) has improved due to the introduction of a simple standard operating procedure. Discrepancies in diagnosis and staging remain, but rapid review CPR allows clinicians to modify treatment if required. Benefits of CPR have been clearly demonstrated; it should be considered for tumor trials.

    18. Pediatric Oncology
      You have free access to this content
      Predictors of inactive lifestyle among adult survivors of childhood cancer : A report from the Childhood Cancer Survivor Study (pages 1984–1994)

      Kirsten K Ness, Wendy M. Leisenring, Sujuan Huang, Melissa M. Hudson, James G. Gurney, Kimberly Whelan, Wendy L. Hobbie, Gregory T. Armstrong, Leslie L. Robison and Kevin C. Oeffinger

      Article first published online: 17 FEB 2009 | DOI: 10.1002/cncr.24209

      For this report, the authors documented the physical activity patterns in the Childhood Cancer Survivor Study cohort, compared physical activity patterns between survivors and siblings, and evaluated the association between diagnosis, treatment, and demographic/personal factors and the risk of an inactive lifestyle. The results indicated that childhood cancer survivors were less active physically compared with their siblings and with an age- and sex-matched sample.

    19. Radiation Oncology
      You have free access to this content
      Prognostic impact of magnetic resonance imaging-detected cranial nerve involvement in nasopharyngeal carcinoma (pages 1995–2003)

      Lizhi Liu, Shaobo Liang, Li Li, Yanping Mao, Linglong Tang, Li Tian, Xinbiao Liao, Chunyan Cui, Aihua Lin and Jun Ma

      Article first published online: 20 FEB 2009 | DOI: 10.1002/cncr.24201

      Retrospective analysis was made of the magnetic resonance images and medical records of 924 consecutive patients with newly diagnosed nasopharyngeal carcinoma (NPC). Magnetic resonance imaging-detected cranial nerve involvement was found to have a negative impact on prognosis independent of lesion localization and symptoms.

    20. Symptom Control and Palliative Care
      You have free access to this content
      Impact of delirium and recall on the level of distress in patients with advanced cancer and their family caregivers (pages 2004–2012)

      Eduardo Bruera, Shirley H. Bush, Jie Willey, Timotheos Paraskevopoulos, Zhijun Li, J. Lynn Palmer, Marlene Z. Cohen, Debra Sivesind and Ahmed Elsayem

      Article first published online: 24 FEB 2009 | DOI: 10.1002/cncr.24215

      The majority of patients with advanced cancer who have recovered from delirium recalled the episode. Family caregivers recalled more delirium symptoms than patients, and both these groups expressed a high level of associated distress.

    21. You have free access to this content
      Supportive versus palliative care: What's in a name? : A survey of medical oncologists and midlevel providers at a comprehensive cancer center (pages 2013–2021)

      Nada Fadul, Ahmed Elsayem, J. Lynn Palmer, Egidio Del Fabbro, Kay Swint, Zhijun Li, Valerie Poulter and Eduardo Bruera

      Article first published online: 20 FEB 2009 | DOI: 10.1002/cncr.24206

      This study determined the perception of the impact of the name palliative care compared with supportive care on patient referral as indicated by referrals at specific times in the cancer illness trajectory.

  5. Errata

    1. Top of page
    2. News
    3. Editorial
    4. Review Articles
    5. Original Articles
    6. Errata
    1. You have free access to this content
      Erratum (page 2022)

      Article first published online: 11 MAR 2009 | DOI: 10.1002/cncr.24275

      This article corrects:

      Frequency, risk factors, and trends for venous thromboembolism among hospitalized cancer patients

      Vol. 113, Issue 1, 223–224, Article first published online: 28 APR 2008

    2. You have free access to this content
      Erratum (page 2023)

      Article first published online: 11 MAR 2009 | DOI: 10.1002/cncr.24274

      This article corrects:
    3. You have free access to this content
      Erratum (page 2024)

      Article first published online: 11 MAR 2009 | DOI: 10.1002/cncr.24273

      This article corrects:

      Expression of epidermal growth factor receptor in esophageal and esophagogastric junction adenocarcinomas

      Vol. 109, Issue 4, 658–667, Article first published online: 8 JAN 2007

SEARCH

SEARCH BY CITATION