Delays in diagnosis and bladder cancer mortality (pages 5235–5242)
Brent K. Hollenbeck, Rodney L. Dunn, Zaojun Ye, John M. Hollingsworth, Ted A. Skolarus, Simon P. Kim, James E. Montie, Cheryl T. Lee, David P. Wood Jr. and David C. Miller
Article first published online: 3 NOV 2010 | DOI: 10.1002/cncr.25310
To determine whether opportunities for improving bladder cancer outcomes may exist upstream from the diagnosis, the authors used national cancer registry data to measure the relation between a delay in diagnosis and a patient's risk of death. Among patients who had hematuria in the year before their bladder cancer diagnosis, a 9-month delay in diagnosis was associated with a nearly 30% greater risk of death from the disease, independent of cancer grade or stage, compared with patients who were diagnosed within 3 months of their first hematuria claim (adjusted hazard ratio, 1.29 [1.14-1.45]).