Evaluating the ability to detect change of health-related quality of life in children with Hodgkin disease (pages 1608–1614)
Robert J Klaassen, Murray Krahn, Isabelle Gaboury, Joanna Hughes, Ronald Anderson, Paul Grundy, S. Kaiser Ali, Lawrence Jardine, Oussama Abla, Mariana Silva, Dorothy Barnard and Mario Cappelli
Article first published online: 8 FEB 2010 | DOI: 10.1002/cncr.24883
We evaluated 4 different health-related quality of life measures prospectively to determine their ability to detect change over time: the Health Utilities Index Mark 2 and Mark 3, the Pediatric Quality of Life Inventory (PedsQL) 4.0 Generic Core and Cancer Module, the EuroQol EQ-5D visual analogue scale (EuroQol), and the Lansky Play-Performance Scale. All of the measures were able to detect change in a diverse group of children with Hodgkin disease, with the PedsQL and the EuroQol appearing to be the most sensitive to change.