A combined molecular-pathologic score improves risk stratification of thyroid papillary microcarcinoma (pages 2069–2077)
Leo A. Niemeier, Haruko Kuffner Akatsu, Chi Song, Sally E. Carty, Steven P. Hodak, Linwah Yip, Robert L. Ferris, George C. Tseng, Raja R. Seethala, Shane O. LeBeau, Michael T. Stang, Christopher Coyne, Jonas T. Johnson, Andrew F. Stewart and Yuri E. Nikiforov
Version of Record online: 31 AUG 2011 | DOI: 10.1002/cncr.26425
Thyroid papillary microcarcinoma (TPMC) is a common thyroid tumor with clinical behavior that is difficult to predict. A combined molecular-pathologic risk stratification model based on BRAF mutation status and 3 histopathologic features is a better predictor of extrathyroid spread of TPMC than either mutational or histopathologic findings alone.