A fluorescence in situ hybridization-based assay for improved detection of lung cancer cells in bronchial washing specimens (pages 306–315)
Irina A. Sokolova, Lukas Bubendorf, Anna O'Hare, Mona S. Legator, Kris K.B. Jacobson, Bruno Grilli B.S., Peter Dalquen, Kevin C. Halling, Michael Tamm, Steven A. Seelig and Larry E. Morrison
Article first published online: 9 JUL 2002 | DOI: 10.1002/cncr.10720
Using a fluorescence in situ hybridization assay (FISH), genetic changes can be detected successfully in malignant cells recovered from the bronchial washing specimens of lung carcinoma patients. This finding indicates a potential utility of the FISH assay as an adjunct to bronchial washing cytology in routine clinical practice.