Breast cancer genetics in African Americans (pages 236–245)
Olufunmilayo I. Olopade, James D. Fackenthal, Georgia Dunston, Michael A. Tainsky, Francis Collins and Carolyn Whitfield-Broome
Article first published online: 18 DEC 2002 | DOI: 10.1002/cncr.11019
BRCA1 and BRCA2 mutations occur in a number of African-American and African families but only a few mutations are recurrent and suggestive of a common ancestry. Therefore, genetic testing should involve searching for mutations in the entire coding region and flanking sequences of both genes.