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Cancer Cytopathology

Cover image for Cancer Cytopathology

25 February 2003

Volume 99, Issue 1

Pages 1–67

Currently known as: Cancer Cytopathology

  1. Editorial

    1. Top of page
    2. Editorial
    3. Original Articles
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      Public expectations, achievable cervical screening sensitivity, and the standard of practice (pages 1–3)

      R. Marshall Austin

      Version of Record online: 30 JAN 2003 | DOI: 10.1002/cncr.11103

      The review of the sensitivity of the Papanicolaou (Pap) smear reminds researchers of the major ambiguities that remain in assessing the vital issues of overall Pap screening sensitivity, assessing comparative accuracy among individual laboratories, and assessing adherence to “the standard of practice.”

  2. Original Articles

    1. Top of page
    2. Editorial
    3. Original Articles
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      Urbanization and the incidence of abnormalities of squamous and glandular epithelium of the cervix (pages 4–8)

      Mathilde E. Boon, Hedda H. van Ravenswaay Claasen, Roelof P. van Westering and Lambrecht P. Kok

      Version of Record online: 5 DEC 2002 | DOI: 10.1002/cncr.10924

      In The Netherlands, the incidences of all grades of squamous and glandular abnormalities of the epithelium of the uterine cervix are lowest in the villages and highest in a large city.

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      Metaanalysis of the accuracy of rapid prescreening relative to full screening of pap smears (pages 9–16)

      Marc Arbyn, Ulrich Schenck, Erin Ellison and Anton Hanselaar

      Version of Record online: 10 DEC 2002 | DOI: 10.1002/cncr.10921

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      Rapid prescreening has a high yield for severe dysplasia and it shows diagnostic properties that support its use as a quality control procedure in cytologic laboratories. Rapid prescreening, just as rapid reviewing, appears to be superior to full reviewing of a 10% random sample of negative slides.

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      Long microvilli of mesothelioma are conspicuous in pleural effusions processed by Ultrafast Papanicolaou stain (pages 17–22)

      Grace C. H. Yang

      Version of Record online: 26 NOV 2002 | DOI: 10.1002/cncr.10920

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      Long microvilli of mesothelioma in pleural effusion are observed by light microscopy by creating retraction halos during cytologic processing. This may aid the differentiation of mesothelioma from mesothelial hyperplasia and adenocarcinoma before ancillary studies are performed.

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      Cytologic features of the nested variant of urothelial carcinoma : A study of seven cases (pages 23–27)

      Marina Cardillo, Victor E. Reuter and Oscar Lin

      Version of Record online: 25 NOV 2002 | DOI: 10.1002/cncr.10955

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      The nested variant of urothelial carcinoma (NVUC) has characteristic cytologic features. In the current study, the authors analyzed urine cytology specimens from patients with NVUC and examined the possible differential diagnoses.

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      Cytologic features of round cell liposarcoma : A report on five patients (pages 28–32)

      Blanca Vicandi, José Jiménez-Heffernan, Pilar López-Ferrer, Pilar González-Peramato and José M. Viguer

      Version of Record online: 5 DEC 2002 | DOI: 10.1002/cncr.10925

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      The cytologic appearance of round cell liposarcoma is unusual compared with other liposarcomas. Nevertheless, cytology shows characteristic findings that, in an adequate clinical context, may lead to a correct diagnosis.

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      Cytologic and immunocytochemical findings of anaplastic large cell lymphoma : Analysis of ten fine-needle aspiration specimens over a 9-year period (pages 33–43)

      Wai-Kuen Ng, Philip Ip, Carolyn Choy and Robert J. Collins

      Version of Record online: 25 NOV 2002 | DOI: 10.1002/cncr.10922

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      In the current study, the authors review the fine-needle aspiration cytology and immunocytochemical findings of anaplastic large cell lymphoma. Recognition of its distinctive morphologic variants, together with the proper application of ancillary investigations, helps clinicians to arrive at a definitive cytologic diagnosis. ALK immunostaining, which provides important prognostic information, also can be applied to cytology samples.

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      Cytologic criteria for well differentiated adenocarcinoma of the pancreas in fine-needle aspiration biopsy specimens (pages 44–50)

      Fan Lin and Gregg Staerkel

      Version of Record online: 12 DEC 2002 | DOI: 10.1002/cncr.11012

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      Fine needle aspiration biopsy (FNAB) of pancreatic lesions has become popular to establish a tissue diagnosis before chemotherapy and/or surgery. The diagnosis of well differentiated pancreatic adenocarcinoma can be made in FNAB specimens by the observance of anisonucleosis, nuclear membrane irregularity, nuclear crowding/overlapping/three-dimensionality, and nuclear enlargement.

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      The use of CDKN2A deletion as a diagnostic marker for malignant mesothelioma in body cavity effusions (pages 51–56)

      Peter B. Illei, Marc Ladanyi, Valerie W. Rusch and Maureen F. Zakowski

      Version of Record online: 27 NOV 2002 | DOI: 10.1002/cncr.10923

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      Differentiating between benign reactive mesothelial cells and malignant mesothelial cells in serous effusions is difficult and results in an unusually high false negative rate. The detection of homozygous CDKN2A deletion by fluorescence in situ hybridization can be helpful in confirming a diagnosis of mesothelioma in this setting.

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      Human papillomavirus typing and DNA ploidy determination of squamous intraepithelial lesions in liquid-based cytologic samples (pages 57–62)

      Reinhard Bollmann, Gábor Méhes, Robert Torka, Norbert Speich, Christoph Schmitt and Magdolna Bollmann

      Version of Record online: 26 NOV 2002 | DOI: 10.1002/cncr.10953

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      Human papillomavirus typing and DNA measurements help in the objectivation of cytologic atypia. Both can be performed efficiently from the same liquid-based cytologic samples.

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      Surface, core, and X genes of hepatitis B virus in hepatocellular carcinoma : An in situ hybridization study (pages 63–67)

      Rudrapatna S. Jayshree, Hema Sridhar and Gayatri M. Devi

      Version of Record online: 27 NOV 2002 | DOI: 10.1002/cncr.10954

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      Hepatitis B virus (HBV) is an important contributing factor in the etiology of hepatocellular carcinoma (HCC) in South India. By nonisotopic in situ hybridization, the S gene of the virus was the most prevalent followed by the X and C genes in HCC. Only integrated forms of the viral DNA were observed.

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