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Cancer Cytopathology

Cover image for Cancer Cytopathology

25 April 2003

Volume 99, Issue 2

Pages 69–127

Currently known as: Cancer Cytopathology

  1. Contemporary Issue

    1. Top of page
    2. Contemporary Issue
    3. Original Article
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      Should cytopathologists stop reporting follicular neoplasms on fine-needle aspiration of the thyroid? : Diagnosis and histologic follow-up of 147 cases (pages 69–74)

      Grace C. H. Yang, Doreen Liebeskind and Albert V. Messina

      Version of Record online: 30 JAN 2003 | DOI: 10.1002/cncr.10957

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      In the current study, using abundant blood as the diagnostic clue, a total of 246 follicular neoplasms were diagnosed of 2667 thyroid fine-needle aspiration (FNA) specimens (9.2%). Histologic follow-up was available for 147 cases and demonstrated 5 widely invasive follicular carcinomas (3.4%), 10 minimally invasive follicular carcinomas (6.8%), 8 cases of the follicular variant of papillary carcinoma (5.4%), 92 cases of follicular adenoma (62.6%), and 32 cases of nonneoplastic nodules (21.8%). It is our opinion that cytopathologists should continue to report follicular neoplasms detected on FNA of the thyroid.

  2. Original Article

    1. Top of page
    2. Contemporary Issue
    3. Original Article
    1. Gynecologic Cytopathology

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      Oral contraceptive pills are associated with artifacts in ThinPrep Pap smears that mimic low-grade squamous intraepithelial lesions (pages 75–82)

      Carl Morrison, Patricia Prokorym, Clara Piquero, Paul E. Wakely Jr. and Gerard J. Nuovo

      Version of Record online: 12 DEC 2002 | DOI: 10.1002/cncr.11056

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      The ThinPrep technique induces cytologic changes that mimic low-grade squamous intraepithelial lesions. These changes are more evident in young women using oral contraceptive pills than in women not using oral contraceptive pills.

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      Impact of the AutoPap (currently focalpoint) primary screening system location guide use on interpretation time and diagnosis (pages 83–88)

      Guglielmo Ronco, Clemente Vineis, Gioia Montanari, Renzo Orlassino, Franca Parisio, Sergio Arnaud, Ester Berardengo, Tiziana Fabbrini and Nereo Segnan

      Version of Record online: 13 DEC 2002 | DOI: 10.1002/cncr.11057

      In the current study the authors compared the diagnosis provided on the basis of the areas marked by PapMaps (the location guide provided by AutoPap) with conventional manual interpretation. PapMaps showed good sensitivity for selecting abnormal slides. The latter require full examination: detailed diagnosis based only on areas marked by PapMaps could lead to under-grading. Use of PapMaps resulted in a substantial reduction in interpretation time.

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      Stability of archived liquid-based cervical cytologic specimens (pages 89–96)

      Philip E. Castle, Diane Solomon, Allan Hildesheim, Rolando Herrero, M. Concepcion Bratti, Mark E. Sherman, Ana Cecilia Rodriguez, Mario Alfaro, Martha L. Hutchinson, S. Terence Dunn, Jane Kuypers and Mark Schiffman

      Version of Record online: 30 JAN 2003 | DOI: 10.1002/cncr.11058

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      Cervical specimens archived in PreservCyt® underwent partial DNA and cytologic degradation after several years of storage, which may limit their use for research.

    4. Non-Gynecologic Cytopathology

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      Nipple aspirate fluid cytology in breast carcinoma (pages 97–104)

      Savitri Krishnamurthy, Nour Sneige, Patricia A. Thompson, Sylvie M. Marcy, S. Eva Singletary, Massimo Cristofanilli, Kelly K. Hunt and Henry M. Kuerer

      Version of Record online: 16 DEC 2002 | DOI: 10.1002/cncr.10958

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      Nipple aspirate fluid (NAF) cytology is not a sensitive test for detecting invasive breast carcinoma. Atypical cytology in NAF is associated with papillary lesions in the underlying breast.

    5. Fine-Needle Aspiration

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      Fine-needle aspiration biopsy cytology of malignant neoplasms of the sinonasal tract : A review of 22 primary and metastatic tumors (pages 105–112)

      Jay C. Helsel, Ricardo H. Bardales and Perkins Mukunyadzi

      Version of Record online: 30 JAN 2003 | DOI: 10.1002/cncr.10956

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      The sinonasal tract is home to a diverse range of malignant primary and metastatic neoplasms. These neoplasms can be sampled by fine-needle aspiration. Cytologic evaluation, with the aid of immunohistochemistry, can lead to an accurate cytologic diagnosis.

    6. Analytical and Quantitative Cytopathology

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      Determination of features indicating progression in atypical squamous cells with undetermined significance : Human papillomavirus typing and DNA ploidy analysis from liquid-based cytologic samples (pages 113–117)

      Reinhard Bollmann, Gábor Méhes, Robert Torka, Norbert Speich, Christoph Schmitt and Magdolna Bollmann

      Version of Record online: 16 DEC 2002 | DOI: 10.1002/cncr.11010

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      Human papillomavirus typing and DNA content measurements may delineate a distinct group of atypical squamous cells of undetermined significance (ASCUS). Our preliminary data suggest that ASCUS cases with high-risk HPV positivity and highly amploid cells are at an elevated risk to develop cancer.

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      Fine-needle aspiration biopsy and flow cytometry immunophenotyping of lymphoid and myeloproliferative disorders of the spleen (pages 118–127)

      Pio Zeppa, Marco Picardi, Gilda Marino, Giancarlo Troncone, Franco Fulciniti, Antonio Vetrani, Bruno Rotoli and Lucio Palombini

      Version of Record online: 13 DEC 2002 | DOI: 10.1002/cncr.11011

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      Flow cytometry typing is a useful tool in the cytologic diagnosis of lymph node disorders. This technique also enhances the diagnostic power of fine-needle aspiration biopsy of the spleen in lymphoid and myeloproliferative processes.

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