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Cancer Cytopathology

Cover image for Cancer Cytopathology

25 April 2009

Volume 117, Issue 2

Pages 73–147

  1. Contemporary Issue

    1. Top of page
    2. Contemporary Issue
    3. Contemporary Issues
    4. Original Articles
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      NA cohort study of thyroid cancer and other thyroid diseases after the Chernobyl accident : Cytohistopathologic correlation and accuracy of fine-needle aspiration biopsy in nodules detected during the first screening in Ukraine (1998-2000) (pages 73–81)

      Yuriy Bozhok, Ellen Greenebaum, Tetyana I. Bogdanova, Robert J. McConnell, Anna Zelinskaya, Alina V. Brenner, Lyudmyla Y. Zurnadzhy, Lydia Zablotska, Mykola D. Tronko and Maureen Hatch

      Version of Record online: 17 FEB 2009 | DOI: 10.1002/cncy.20002

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      The Ukrainian-American Cohort Study was established to evaluate the risk of thyroid disorders in a group exposed as children and adolescents to 131I by the Chernobyl accident. In this study, among children and adolescents who were exposed to 131I after Chernobyl and evaluated 12 to 14 years later, thyroid cytology had a sensitivity and predictive value similar to those reported in unexposed populations.

  2. Contemporary Issues

    1. Top of page
    2. Contemporary Issue
    3. Contemporary Issues
    4. Original Articles
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      Mandatory second opinion in cytopathology (pages 82–91)

      Nathan Lueck, Chris Jensen, Michael B. Cohen and Jamie A. Weydert

      Version of Record online: 23 FEB 2009 | DOI: 10.1002/cncy.20019

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      Second opinion review of outside cytology material at the University of Iowa Carver College of Medicine yielded 7.4% cases with major diagnostic disagreements. Some of these major diagnostic disagreements resulted in a change in clinical management, suggesting that a mandatory second opinion policy is an important part of patient care.

  3. Original Articles

    1. Top of page
    2. Contemporary Issue
    3. Contemporary Issues
    4. Original Articles
    1. Gyncologic Cytopathology

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      Clinical significance of the diagnosis of low-grade squamous intraepithelial lesion, cannot exclude high-grade squamous intraepithelial lesion (pages 92–100)

      Mariam Alsharif, Klint Kjeldahl, Colleen Curran, Shelby Miller, H. Evin Gulbahce and Stefan E. Pambuccian

      Version of Record online: 17 FEB 2009 | DOI: 10.1002/cncy.20004

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      Low-grade squamous intraepithelial lesion, cannot exclude high-grade squamous intraepithelial lesion is an unusual Papanicolaou test diagnosis and, in this study, was found to be associated with a histologic rate of cervical intraepithelial neoplasia type 2 (CIN-2)/CIN-3+ similar to the rate of atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion, warranting similar management.

    2. Fine-Needle Aspiration

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      Pseudocyst of the pancreas : The role of cytology and special stains for mucin (pages 101–107)

      Elvira Gonzalez Obeso, Erin Murphy, William Brugge and Vikram Deshpande

      Version of Record online: 20 FEB 2009 | DOI: 10.1002/cncy.20000

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      The authors explored the cytomorphologic features of pseudocyst of the pancreas and evaluated the role of Alcian blue and mucicarmine stains in the cytologic evaluation of pancreatic cysts. The findings indicated that special stains for mucin do not distinguish pseudocysts from neoplastic mucinous cysts.

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      p16INK4A immunohistochemical staining may be helpful in distinguishing branchial cleft cysts from cystic squamous cell carcinomas originating in the oropharynx (pages 108–119)

      Reetesh K. Pai, Julianna Erickson, Nader Pourmand and Christina S. Kong

      Version of Record online: 10 FEB 2009 | DOI: 10.1002/cncy.20001

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      p16INK4A immunohistochemistry may be helpful in localizing tumor origin of metastatic head and neck squamous cell carcinoma to the oropharynx, but it is not useful in differentiating between keratinizing squamous cell carcinoma and branchial cleft cysts.

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      A technique to improve diagnostic information from fine-needle aspirations : Immunohistochemistry on cytoscrape (pages 120–127)

      Birgit Guldhammer Skov, Katalin Kiss, Julie Ramsted and Dorte Linnemann

      Version of Record online: 10 FEB 2009 | DOI: 10.1002/cncy.20005

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      Cytoscrapes made from fine-needle aspiration improved the clinically relevant information, because the aspirated material could be used by ancillary methods, including immunohistochemistry.

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      Synovial sarcoma: Diagnosis on fine-needle aspiration by morphology and molecular analysis (pages 128–136)

      Radhika Srinivasan, Upasana Gautam, Ruchi Gupta, Arvind Rajwanshi and Rakesh Kumar Vasistha

      Version of Record online: 6 MAR 2009 | DOI: 10.1002/cncy.20006

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      Synovial sarcoma (SS) can be diagnosed on fine-needle aspiration (FNA) cytology by a combined morphological and reverse transcriptase polymerase chain reaction (RT-PCR) analysis.

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      Breast fine-needle aspiration samples reported as “proliferative breast lesion”: Clinical utility of the subcategory “proliferative breast lesion with atypia” (pages 137–147)

      Chengquan Zhao, Anwar Raza, Sue E. Martin, Jiangqiu Pan, Timothy S. Greaves and Camilla J. Cobb

      Version of Record online: 20 FEB 2009 | DOI: 10.1002/cncy.20003

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      Because breast lesions diagnosed as proliferative breast lesion on fine-needle aspiration FNA include significant proportions of both benign and malignant entities on histology, a subcategory of proliferative breast lesion with atypia may be helpful in dividing patients into groups needing immediate intervention and patients who can be managed more conservatively. In this study, the authors report whether a subcategory of “proliferative breast lesion with atypia” was achievable and whether this subcategory has management utility.

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