UbcH10 expression on thyroid fine-needle aspirates (pages 157–165)
Eliana Guerriero, Angelo Ferraro, Doriana Desiderio, Pierlorenzo Pallante, Maria Teresa Berlingieri, Antonino Iaccarino, Emiliano Palmieri, Lucio Palombini, Alfredo Fusco and Giancarlo Troncone
Version of Record online: 18 MAY 2010 | DOI: 10.1002/cncy.20046
The authors recently identified UbcH10 as a novel cancer marker useful in the diagnosis and prognosis of several human neoplasms, including thyroid cancer. In the present study, they demonstrate that quantitative reverse transcriptase polymerase chain reaction analysis, rather than immunohistochemistry, of UbcH10 expression is useful to increase detection of malignancy in follicular neoplasm/suspicious for malignancy routine thyroid fine-needle aspirate.