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Cancer Cytopathology

Cover image for Cancer Cytopathology

25 June 2010

Volume 118, Issue 3

Pages 113–172

  1. CytoSource

    1. Top of page
    2. CytoSource
    3. Editorial
    4. Original Articles
    1. You have free access to this content
    2. You have free access to this content
  2. Editorial

    1. Top of page
    2. CytoSource
    3. Editorial
    4. Original Articles
    1. You have free access to this content
      Telecytopathology for immediate evaluation of fine-needle aspiration specimens (pages 115–118)

      Keith J. Kaplan

      Article first published online: 11 MAY 2010 | DOI: 10.1002/cncy.20079

      Telepathology is an evolving area of telemedicine. Guidelines for primary opinion telepathology should be driven by best practices in conventional laboratory procedures. See also pages 119-26.

  3. Original Articles

    1. Top of page
    2. CytoSource
    3. Editorial
    4. Original Articles
    1. You have free access to this content
      Telecytopathology for immediate evaluation of fine-needle aspiration specimens (pages 119–126)

      Mariam Alsharif, Jamie Carlo-Demovich, Caroline Massey, James E. Madory, David Lewin, Ana-Maria Medina, Rosemary Recavarren, Patricia M. Houser and Jack Yang

      Article first published online: 28 MAY 2010 | DOI: 10.1002/cncy.20074

      Telecytopathology is an efficient alternative to rapid on-site evaluation for initial assessment of fine-needle aspiration samples. It has a similar diagnostic accuracy, and can be used to support trainees located at distant sites.

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      Value of cytology in the intraoperative assessment of ovarian tumors : A review of 402 cases and comparison with frozen section diagnosis (pages 127–136)

      Colin J. R. Stewart, Barbara A Brennan, Eleanor Koay, Anup Naran and Sukeerat Ruba

      Article first published online: 21 APR 2010 | DOI: 10.1002/cncy.20073

      Cytology preparations provide a useful adjunct to frozen section in the intraoperative assessment of ovarian tumors although they do not improve the overall diagnostic accuracy.

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      The application of cytogenetics and fluorescence in situ hybridization to fine-needle aspiration in the diagnosis and subclassification of renal neoplasms (pages 137–145)

      Michael H. Roh, Paola Dal Cin, Stuart G. Silverman and Edmund S. Cibas

      Article first published online: 28 APR 2010 | DOI: 10.1002/cncy.20077

      Fine-needle aspirates of renal masses are amenable to analysis by conventional karyotyping and fluorescence in situ hybridization (FISH). Cytogenetics and FISH can serve as adjuncts in the diagnosis and subclassification of renal neoplasms.

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      p16INK4a is superior to high-risk human papillomavirus testing in cervical cytology for the prediction of underlying high-grade dysplasia (pages 146–156)

      Panduka Samarawardana, Donna L. Dehn, Meenakshi Singh, Douglas Franquemont, Chesney Thompson, Loretta Gaido, Kathleen C. Torkko, Petra Homer, Stephanie Burke, Matthew A. Titmus, Vipul Nayi and Kenneth R. Shroyer

      Article first published online: 5 MAY 2010 | DOI: 10.1002/cncy.20078

      An optimized test for p16INK4a in cervical cytology specimens has superior specificity but similar sensitivity to high-risk human papillomavirus testing to predict underlying high-grade cervical intraepithelial neoplasia in patients who are referred for colposcopy.

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      UbcH10 expression on thyroid fine-needle aspirates (pages 157–165)

      Eliana Guerriero, Angelo Ferraro, Doriana Desiderio, Pierlorenzo Pallante, Maria Teresa Berlingieri, Antonino Iaccarino, Emiliano Palmieri, Lucio Palombini, Alfredo Fusco and Giancarlo Troncone

      Article first published online: 18 MAY 2010 | DOI: 10.1002/cncy.20046

      The authors recently identified UbcH10 as a novel cancer marker useful in the diagnosis and prognosis of several human neoplasms, including thyroid cancer. In the present study, they demonstrate that quantitative reverse transcriptase polymerase chain reaction analysis, rather than immunohistochemistry, of UbcH10 expression is useful to increase detection of malignancy in follicular neoplasm/suspicious for malignancy routine thyroid fine-needle aspirate.

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      Classifying B-cell non-Hodgkin lymphoma by using MIB-1 proliferative index in fine-needle aspirates (pages 166–172)

      Abdullah E. Ali, Eric K. Morgen, William R. Geddie, Scott L. Boerner, Christine Massey, Denis J. Bailey and Gilda da Cunha Santos

      Article first published online: 13 MAY 2010 | DOI: 10.1002/cncy.20075

      MIB-1 immunohistochemistry for the assessment of proliferative index (PI) on cytospins from lymph node fine-needle aspirates can help to stratify B-cell non-Hodgkin lymphoma using cutpoints established for separating indolent (<38%), aggressive (≥38% to ≤80.1%) and highly aggressive (>80.1%). MIB-1 PI significantly correlated with increase in tumor aggressiveness.

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