Noninvasive detection of aneuploid cells in laryngeal epithelial precursor lesions (pages 235–246)
Tali Shani, Adi Primov-Fever, Michael Wolf, Bruria Shalmon, Ninette Amarglio, Luba Trakhtenbrot and Abraham Hirshberg
Article first published online: 6 MAY 2011 | DOI: 10.1002/cncy.20157
The objective of this study was to investigate the presence of chromosomal numerical aberrations in cells that were collected noninvasively from laryngeal lesions in samples that were analyzed simultaneously for morphology and fluorescence in situ hybridization. The results suggested that this technique can augment the clinical examination in predicting the nature of laryngeal lesions, avoiding unnecessary surgical interventions.