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Cancer Cytopathology

Cover image for Vol. 119 Issue 5

25 October 2011

Volume 119, Issue 5

Pages 291–354

  1. CytoSource

    1. Top of page
    2. CytoSource
    3. Review Articles
    4. Commentaries
    5. Original Articles
    6. Correspondence
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    2. You have free access to this content
  2. Review Articles

    1. Top of page
    2. CytoSource
    3. Review Articles
    4. Commentaries
    5. Original Articles
    6. Correspondence
    1. You have free access to this content
      Cytologic-histologic correlation (pages 293–309)

      Stephen S. Raab and Dana M. Grzybicki

      Article first published online: 5 JUL 2011 | DOI: 10.1002/cncy.20165

      The process of cytologic-histologic correlation is highly valuable to the fields of both cytopathology and surgical pathology, because correlation provides a wealth of data that may be used to improve diagnostic testing and screening processes. The future of correlation lies in the standardization of methods, the development of more formal and rigorous root cause analysis processes to determine system components underlying correlation discrepancies, and the active use of correlation data to redesign testing and screening processes for quality and patient safety improvement.

  3. Commentaries

    1. Top of page
    2. CytoSource
    3. Review Articles
    4. Commentaries
    5. Original Articles
    6. Correspondence
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      Coding changes in the United States front and center : Implications for cytopathology (pages 310–314)

      Diane Davis Davey and Margaret Havens Neal

      Article first published online: 6 MAY 2011 | DOI: 10.1002/cncy.20159

      Several published coding changes effective in 2011 will contribute to changes in cytopathology payments. A new code for the additional immediate evaluation of fine-needle aspiration specimens is now operative and will be favorable to laboratories, whereas the new dedicated urine in situ hybridization codes will result in lower laboratory payments.

  4. Original Articles

    1. Top of page
    2. CytoSource
    3. Review Articles
    4. Commentaries
    5. Original Articles
    6. Correspondence
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      The impact of implementation of the Bethesda System for Reporting Thyroid Cytopathology on the quality of reporting, “risk” of malignancy, surgical rate, and rate of frozen sections requested for thyroid lesions (pages 315–321)

      Amanda Crowe, Ami Linder, Omar Hameed, Chura Salih, Janie Roberson, Jonathon Gidley and Isam A. Eltoum

      Article first published online: 12 JUL 2011 | DOI: 10.1002/cncy.20174

      Implementation of the Bethesda System for Reporting Thyroid Cytopathology improves the quality of reporting by lowering the number of ambiguous and implicit diagnoses and decreases the overall surgery rates, particularly for benign lesions, but appears to have no effect on thyroid fine-needle aspiration accuracy, false-positive rates, or the frequency of intraoperative consultations.

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      Subclassification of atypical cells of undetermined significance in direct smears of fine-needle aspirations of the thyroid : Distinct patterns and associated risk of malignancy (pages 322–327)

      Andrew A. Renshaw

      Article first published online: 25 MAR 2011 | DOI: 10.1002/cncy.20154

      The majority of AUS cases in thyroid FNA can be subcategorized into 5 different patterns, all with associated significant risk of malignancy. “Atrophic” microfollicles are a significant risk factor for malignancy and should not be diagnosed as benign on the basis of lack of cytologic atypia.

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      The evolving role of axillary lymph node fine-needle aspiration in the management of carcinoma of the breast (pages 328–334)

      Martin C. Chang, Pavel Crystal and Terence J. Colgan

      Article first published online: 22 MAR 2011 | DOI: 10.1002/cncy.20152

      With advances in the management of breast carcinoma, axillary lymph node FNA is not only a major determinant of pathologic staging but also of surgical and medical treatment.

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      Comparison of the expression levels of napsin A, thyroid transcription factor-1, and p63 in nonsmall cell lung cancer using cytocentrifuged bronchial brushings (pages 335–345)

      Emiko Aikawa, Akihiko Kawahara, Satoshi Hattori, Tomohiko Yamaguchi, Hideyuki Abe, Tomoki Taira, Koichi Azuma and Masayoshi Kage

      Article first published online: 29 JUN 2011 | DOI: 10.1002/cncy.20162

      Immunostaining of bronchial brushings fixed with CytoRich Red was useful in determining histologic types in nonsmall cell lung cancer (NSCLC). The panels of Napsin A, thyroid transcription factor-1 (TTF-1), and p63 were effective in identifying histologic type in NSCLC, and a combination of either Napsin A and p63 or TTF-1 and p63 should be chosen, depending on morphology.

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      Diagnostic value of metabolic phenotypes in malignant pleural effusions : Expression of GLUT1 and CAIX by immunocytochemistry (pages 346–353)

      Nai-Ding Liao, Jiunn-Min Shieh and Wen-Ying Lee

      Article first published online: 25 MAR 2011 | DOI: 10.1002/cncy.20153

      Immunocytochemical staining for GLUT1 and CAIX, the hallmarks of metabolic change in cancer cells, could be a complementary tool for the detection of malignant pleural effusions. A combination of GLUT1 and CAIX immunocytochemical staining can provide a higher diagnostic performance.

  5. Correspondence

    1. Top of page
    2. CytoSource
    3. Review Articles
    4. Commentaries
    5. Original Articles
    6. Correspondence
    1. You have free access to this content

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