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Cancer Cytopathology

Cover image for Vol. 120 Issue 2

25 April 2012

Volume 120, Issue 2

Pages 71–141

  1. CytoSource

    1. Top of page
    2. CytoSource
    3. Review Articles
    4. Commentaries
    5. Editorials
    6. Original Articles
    1. You have free access to this content
  2. Review Articles

    1. Top of page
    2. CytoSource
    3. Review Articles
    4. Commentaries
    5. Editorials
    6. Original Articles
    1. You have free access to this content
      The atypical thyroid fine-needle aspiration: Past, present, and future (pages 73–86)

      Massimo Bongiovanni, Jeffrey F. Krane, Edmund S. Cibas and William C. Faquin

      Article first published online: 12 JUL 2011 | DOI: 10.1002/cncy.20178

      Atypia in thyroid aspirates can be problematic. The Bethesda System for Reporting Thyroid Cytopathology has helped to delineate such cases in a meaningful manner through introduction of the atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) category.

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      Cervical screening in England: The past, present, and future (pages 87–96)

      Rebecca Albrow, Henry Kitchener, Nalini Gupta and Mina Desai

      Article first published online: 24 FEB 2012 | DOI: 10.1002/cncy.20203

      This review discusses the events leading up to the establishment of England's National Health Services Cervical Screening Programme, how it has evolved, and the logical next steps for this world-renowned system.

  3. Commentaries

    1. Top of page
    2. CytoSource
    3. Review Articles
    4. Commentaries
    5. Editorials
    6. Original Articles
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      Commentary on “Cervical cancer screening in England: The past, present, and future”: A comparison with Canada (pages 97–101)

      Máire A. Duggan

      Article first published online: 24 FEB 2012 | DOI: 10.1002/cncy.20201

      Cervical cancer screening in Canada is largely opportunistic, and a model of central coordination and peripheral delivery similar to the National Health Services Cervical Screening Programme is not feasible. The future should see full implementation of organized screening in all Canadian provinces, and when combined with the publicly funded human papillomavirus vaccination program of young girls begun in 2008, the result should be even better cancer control.

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      Cervical cytology screening programs: Similarities and differences between the United States and United Kingdom systems (pages 102–104)

      David C. Wilbur

      Article first published online: 24 FEB 2012 | DOI: 10.1002/cncy.20202

      The United States and United Kingdom have cervical cancer screening programs that developed many similar and contrasting characteristics based on circumstances unique to each society. These features, their origins, and potential futures are presented.

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      Cancer screening of the uterine cervix papanicolaou smears versus state-of-the-art human papillomavirus testing (pages 105–107)

      Bryan Knight

      Article first published online: 24 FEB 2012 | DOI: 10.1002/cncy.20200

      The key ingredient for success of England's National Health Service Cytology Screening Programme is quality assurance. Human papillomavirus DNA testing could be introduced as a primary screening tool in the future.

  4. Editorials

    1. Top of page
    2. CytoSource
    3. Review Articles
    4. Commentaries
    5. Editorials
    6. Original Articles
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      The potential for overuse of atypical thyroid diagnoses (pages 108–110)

      Michael Henry

      Article first published online: 16 SEP 2011 | DOI: 10.1002/cncy.20191

      The atypical follicular cell diagnosis in the new Bethesda System for Reporting Thyroid Cytopathology is a heterogeneous category without well-defined cellular criteria and has the potential for overuse. Laboratories should monitor the use of this diagnosis.

  5. Original Articles

    1. Top of page
    2. CytoSource
    3. Review Articles
    4. Commentaries
    5. Editorials
    6. Original Articles
    1. You have free access to this content
      The atypia of undetermined significance/follicular lesion of undetermined significance:malignant ratio : A proposed performance measure for reporting in The Bethesda System for thyroid cytopathology (pages 111–116)

      Jeffrey F. Krane, Paul A. VanderLaan, William C. Faquin and Andrew A. Renshaw

      Article first published online: 14 SEP 2011 | DOI: 10.1002/cncy.20192

      The atypia of undetermined significance/follicular lesion of undetermined significance:malignant (AUS:M) ratio is a useful performance measure for the reporting of thyroid fine-needle aspiration specimens in the Bethesda System. Based on available studies, an AUS:M ratio between 1.0 and 3.0 is recommended.

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      Comparison of 5-tiered and 6-tiered diagnostic systems for the reporting of thyroid cytopathology : A multi-institutional study (pages 117–125)

      Massimo Bongiovanni, Stefano Crippa, Zubair Baloch, Simonetta Piana, Alessandra Spitale, Fabio Pagni, Luca Mazzucchelli, Camillo Di Bella and William Faquin

      Article first published online: 13 OCT 2011 | DOI: 10.1002/cncy.20195

      Standardization of reporting terminology for thyroid fine-needle aspiration (FNA) specimens facilitates communication between pathologists and clinicians. The authors present their institutional experiences using a 5-tiered and a 6-tiered system for reporting thyroid FNA results, and evaluate their efficacy based on the surgical follow-up. Depending on the classification system used, the results can influence the management of patients with a thyroid nodule.

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      Implementation of FocalPoint GS location-guided imaging system : Experience in a clinical setting (pages 126–133)

      Angelique W. Levi, David C. Chhieng, Kevin Schofield, Diane Kowalski and Malini Harigopal

      Article first published online: 25 AUG 2011 | DOI: 10.1002/cncy.20187

      The impact of implementing FocalPoint GS in a routine clinical setting of a gynecologic cytology laboratory is reported. There was an increase in the interpretation of LSIL and ASC-US and a decrease in the EFNF after FPGS implementation.

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      The diagnostic value of cell block as an adjunct to liquid-based cytology of bronchial washing specimens in the diagnosis and subclassification of pulmonary neoplasms (pages 134–141)

      George R. Collins, Jaiyeola Thomas, Neelam Joshi and Songlin Zhang

      Article first published online: 12 JUL 2011 | DOI: 10.1002/cncy.20181

      The use of cell block on bronchial washing specimens as an adjunct to liquid-based cytology improved diagnostic yield, often allowed for the determination of specific tumor histologic types, and provided available material for immunohistochemical and molecular studies. Cell block is useful for the diagnosis of pulmonary neoplasms in this setting, especially in cases with suspicious and atypical diagnoses.

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