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Cancer Cytopathology

Cover image for Vol. 121 Issue 1

January 2013

Volume 121, Issue 1

Pages 1–53

  1. A Note from the Editor

    1. Top of page
    2. A Note from the Editor
    3. Clinician's Corner
    4. Commentaries
    5. Review Articles
    6. Original Articles
    1. You have free access to this content
      Happy new year! (page 1)

      Celeste N. Powers

      Article first published online: 14 JAN 2013 | DOI: 10.1002/cncy.21268

  2. Clinician's Corner

    1. Top of page
    2. A Note from the Editor
    3. Clinician's Corner
    4. Commentaries
    5. Review Articles
    6. Original Articles
    1. You have free access to this content
  3. Commentaries

    1. Top of page
    2. A Note from the Editor
    3. Clinician's Corner
    4. Commentaries
    5. Review Articles
    6. Original Articles
    1. You have full text access to this OnlineOpen article
      “The petals and thorns” of ROSE (rapid on-site evaluation) (pages 4–8)

      Gilda da Cunha Santos, Hyang-Mi Ko, Mauro Ajaj Saieg and William R. Geddie

      Article first published online: 3 JUL 2012 | DOI: 10.1002/cncy.21215

      In this article, the authors discuss the advantages (“petals”) and disadvantages (“thorns”) of rapid on-site evaluation (ROSE) performed for minimally invasive procedures such as computed tomography (CT)-guided and endoscopic-guided fine-needle aspiration with a focus on deep-seated lymph nodes. One of the main advantages is increased diagnostic accuracy. Disadvantages include the need for highly trained professionals and a lack of adequate reimbursement.

  4. Review Articles

    1. Top of page
    2. A Note from the Editor
    3. Clinician's Corner
    4. Commentaries
    5. Review Articles
    6. Original Articles
    1. You have full text access to this OnlineOpen article
      A review of reporting systems and terminology for urine cytology (pages 9–14)

      Christopher L. Owens, Christopher J. VandenBussche, Frances H. Burroughs and Dorothy L. Rosenthal

      Article first published online: 28 NOV 2012 | DOI: 10.1002/cncy.21253

      The authors review the reporting systems that have been introduced in the literature for urinary cytology. Their review highlights the diagnostic categories and criterion for classification of each scheme and how they have evolved as histologic classification has changed and knowledge of the test has improved.

  5. Original Articles

    1. Top of page
    2. A Note from the Editor
    3. Clinician's Corner
    4. Commentaries
    5. Review Articles
    6. Original Articles
    1. You have full text access to this OnlineOpen article
      The Johns Hopkins Hospital template for urologic cytology samples : Part I—Creating the template (pages 15–20)

      Dorothy L. Rosenthal, Christopher J. VandenBussche, Frances H. Burroughs, Srividya Sathiyamoorthy, Hui Guan and Christopher Owens

      Article first published online: 28 NOV 2012 | DOI: 10.1002/cncy.21255

      The authors describe a template for urologic cytology samples that is effective in targeting those patients who need to undergo cystoscopy. Greater than 66% of patients who have biopsy confirmation of high-grade urothelial carcinoma had a preceding cytologic diagnosis of atypical urothelial cells, favor high-grade carcinoma or high-grade urothelial carcinoma.

    2. You have full text access to this OnlineOpen article
      The Johns Hopkins Hospital template for urologic cytology samples : Parts II and III—Improving the predictability of indeterminate results in urinary cytologic samples: an outcomes and cytomorphologic study (pages 21–28)

      Christopher J. VandenBussche, Srividya Sathiyamoorthy, Christopher L. Owens, Frances H. Burroughs, Dorothy L. Rosenthal and Hui Guan

      Article first published online: 28 NOV 2012 | DOI: 10.1002/cncy.21254

      Urinary tract specimens that are diagnosed as highly suspicious for high-grade urothelial carcinoma often contain cells with hyperchromasia, irregular nuclear borders, an increased nucleus-to-cytoplasm ratio, and anisonucleosis. These features have a significant association with high-grade urothelial carcinoma when surveillance, but not hematuria, is an indication for the sample.

    3. You have full text access to this OnlineOpen article
      Prospective analysis of atypical epithelial cells as a high-risk cytologic feature for malignancy in pancreatic cysts (pages 29–36)

      Martha B. Pitman, Kurt A. Yaeger, William R. Brugge and Mari Mino-Kenudson

      Article first published online: 6 NOV 2012 | DOI: 10.1002/cncy.21242

      Cytology is an important component of the preoperative evaluation of patients with pancreatic cysts. The category of high-grade atypical epithelial cells, rather than “positive” (malignant) epithelial cells, is a sensitive, high-risk feature for malignancy with 85% accuracy for detecting pancreatic cysts that require resection.

    4. You have full text access to this OnlineOpen article
      Human pancreatic cancer fusion 2 (HPC2) 1-B3: A novel monoclonal antibody to screen for pancreatic ductal dysplasia (pages 37–46)

      Terry K. Morgan, Karin Hardiman, Christopher L. Corless, Sandra L. White, Robert Bonnah, Henry Van de Vrugt, Brett C. Sheppard, Markus Grompe, Ediz F. Cosar and Philip R. Streeter

      Article first published online: 18 JUL 2012 | DOI: 10.1002/cncy.21223

      The monoclonal antibody human pancreatic cancer fusion 2 (HPC2) 1-B3 immunostains pancreatic intraductal papillary mucinous neoplasms and ductal adenocarcinoma. This marker also appears to be secreted by dysplastic pancreatic cells, which may lead to a new rapid screening assay.

    5. You have full text access to this OnlineOpen article
      Adherence to practice guidelines for atypical glandular cells on cervical cytology (pages 47–53)

      Kathryn E. Sharpless, Cara R. King and Peter F. Schnatz

      Article first published online: 12 JUN 2012 | DOI: 10.1002/cncy.21211

      Compliance with practice guidelines for atypical glandular cells on cervical cytology has improved, but remains suboptimal, especially in women at high risk. Cytopathologist recommendations on cytology reports correlate with the types of evaluations women with atypical glandular cells receive.

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