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Cancer Cytopathology

Cover image for Vol. 123 Issue 1

January 2015

Volume 123, Issue 1

Pages 1–65

  1. CytoSource

    1. Top of page
    2. CytoSource
    3. A Note from The Editor
    4. Cytopathology Help Desk
    5. Commentary
    6. Original Articles
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  2. A Note from The Editor

    1. Top of page
    2. CytoSource
    3. A Note from The Editor
    4. Cytopathology Help Desk
    5. Commentary
    6. Original Articles
    1. You have free access to this content
  3. Cytopathology Help Desk

    1. Top of page
    2. CytoSource
    3. A Note from The Editor
    4. Cytopathology Help Desk
    5. Commentary
    6. Original Articles
    1. You have free access to this content
  4. Commentary

    1. Top of page
    2. CytoSource
    3. A Note from The Editor
    4. Cytopathology Help Desk
    5. Commentary
    6. Original Articles
    1. You have free access to this content
      An historic step for advanced cytopathology training in Canada (pages 7–9)

      Manon Auger, Shahidul Islam and Michele Weir

      Article first published online: 23 SEP 2014 | DOI: 10.1002/cncy.21485

      Advanced cytopathology training has finally obtained official recognition in Canada, having recently been assigned the newly developed status of “Area of Focused Competence” by the Royal College of Physicians and Surgeons of Canada. It is hoped that the trainees who graduate from these programs in cytopathology will be provided with the leadership and consultant skills to allow them to adapt and respond competently to the rapid evolving field of cytopathology.

  5. Original Articles

    1. Top of page
    2. CytoSource
    3. A Note from The Editor
    4. Cytopathology Help Desk
    5. Commentary
    6. Original Articles
    1. You have free access to this content
      Accuracy and risk of malignancy for diagnostic categories in urine cytology at a large tertiary institution (pages 10–18)

      Karen Chau, Lisa Rosen, Constantinos Coutsouvelis, Maly Fenelus, Ryan Brenkert, Melissa Klein, Gary Stone, Stephen Raab, Mohamed Aziz and Rubina Cocker

      Article first published online: 11 NOV 2014 | DOI: 10.1002/cncy.21477

      Our study demonstrates an overall sensitivity and specificity of cytologic diagnoses comparable to those previously reported and slightly higher values for both low-grade urothelial carcinoma of the bladder and high-grade urothelial carcinoma of the upper tract. A higher value for additive sensitivity and a discrete time analysis showing a decline in predicted positive cytology after the fourth cytology suggests that the optimal follow-up should include at least 4 consecutive urine cytology specimens over a time period averaging 22.2 months.

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      Fine-needle aspiration biopsy of secondary neoplasms of the thyroid gland: A multi-institutional study of 62 cases (pages 19–29)

      Marc Pusztaszeri, He Wang, Edmund S. Cibas, Celeste N. Powers, Massimo Bongiovanni, Syed Ali, Kamal K. Khurana, Paul J. Michaels and William C. Faquin

      Article first published online: 4 NOV 2014 | DOI: 10.1002/cncy.21494

      Adenocarcinomas from the kidney, lung, breast, and colon along with squamous cell carcinomas represent the majority of secondary neoplasms of the thyroid gland (SNTGs). Fine-needle aspiration biopsy is a sensitive and accurate method for diagnosing SNTGs; however, diagnostic difficulties can occur, and knowledge of clinical history and judicious application of ancillary studies can increase the sensitivity and accuracy of fine-needle aspiration biopsy for detecting SNTGs.

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      Multiplatform comparison of molecular oncology tests performed on cytology specimens and formalin-fixed, paraffin-embedded tissue (pages 30–39)

      Michael P. Gailey, Aaron A. Stence, Chris S. Jensen and Deqin Ma

      Article first published online: 3 SEP 2014 | DOI: 10.1002/cncy.21476

      Cytology specimens are a cost-effective, reliable source for molecular oncology testing and may save patients from additional procedures when adequate material is available.

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      Low interobserver agreement in cytology grading of mucinous pancreatic neoplasms (pages 40–50)

      Carlie S. Sigel, Marcia Edelweiss, Leung Chu Tong, Joanna Magda, Handy Oen, Keith M. Sigel and Maureen F. Zakowski

      Article first published online: 29 OCT 2014 | DOI: 10.1002/cncy.21492

      Observers showed fair interobserver agreement for grading mucinous pancreatic neoplasms and low interobserver agreement for identifying neoplastic mucin. Knowledge of the cyst fluid carcinoembryonic antigen level was found to modestly improve interobserver agreement for low-grade neoplasms.

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      A cytomorphometric analysis of pulmonary and mediastinal granulomas: Differentiating histoplasmosis from sarcoidosis by fine-needle aspiration (pages 51–58)

      Michael P. Gailey, Matthew E. Keeney and Chris S. Jensen

      Article first published online: 15 OCT 2014 | DOI: 10.1002/cncy.21491

      The majority of cases of histoplasmosis and sarcoidosis can be differentiated by several cytologic parameters, such as the presence of necrosis, the number of granulomas, the morphology of granulomas, and the presence of giant cell infiltrates.

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      Follow-up and clinical significance of unsatisfactory liquid-based Papanicolaou tests (pages 59–65)

      Christopher L. Owens, Diana S.M. Buist, Daniel Peterson, Aruna Kamineni, Sheila Weinmann, Tyler Ross, Andrew E. Williams, Azadeh Stark, Kenneth F. Adams, Chyke A. Doubeni and Terry S. Field

      Article first published online: 23 OCT 2014 | DOI: 10.1002/cncy.21490

      Various clinical factors influence the receipt of guideline-recommended follow-up studies after an unsatisfactory Papanicolaou test. The results of high-risk human papillomavirus testing demonstrate promise for stratifying the risk after an unsatisfactory Papanicolaou test.

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