Cancer Cytopathology

Cover image for Vol. 123 Issue 7

July 2015

Volume 123, Issue 7

Pages i–iv, 385–443

  1. Issue Information

    1. Top of page
    2. Issue Information
    3. CytoSource
    4. Clinician's Corner
    5. Commentary
    6. Original Articles
    7. Erratum
    1. You have free access to this content
      Issue information (pages i–iv)

      Article first published online: 14 JUL 2015 | DOI: 10.1002/cncy.21582

  2. CytoSource

    1. Top of page
    2. Issue Information
    3. CytoSource
    4. Clinician's Corner
    5. Commentary
    6. Original Articles
    7. Erratum
  3. Clinician's Corner

    1. Top of page
    2. Issue Information
    3. CytoSource
    4. Clinician's Corner
    5. Commentary
    6. Original Articles
    7. Erratum
    1. You have free access to this content
  4. Commentary

    1. Top of page
    2. Issue Information
    3. CytoSource
    4. Clinician's Corner
    5. Commentary
    6. Original Articles
    7. Erratum
    1. Evolving role of FNA biopsy in diagnosing lymphoma: Past, present, and future (pages 389–393)

      Nancy P. Caraway

      Article first published online: 27 APR 2015 | DOI: 10.1002/cncy.21551

      Despite being challenged more than a decade ago, fine-needle aspiration biopsy continues to have a valuable role in diagnosing lymphomas. An updated lymphoma classification and several advances in technologies have aided in its increased acceptance and use; however, now is the time to integrate fine-needle aspiration biopsy with ancillary studies and obtain material for potential molecular testing in the routine workup of lymphomas to ensure its continued use in the future.

  5. Original Articles

    1. Top of page
    2. Issue Information
    3. CytoSource
    4. Clinician's Corner
    5. Commentary
    6. Original Articles
    7. Erratum
    1. Microphthalmia transcription factor immunohistochemistry for FNA biopsy of ocular malignant melanoma (pages 394–400)

      Carmen M. Perrino, Jeff F. Wang and Brian T. Collins

      Article first published online: 24 FEB 2015 | DOI: 10.1002/cncy.21531

      This study is an evaluation of immunohistochemistry in the workup of fine-needle aspiration biopsies of ocular malignant melanoma and especially the new marker microphthalmia transcription factor. In addition, we show that microphthalmia transcription factor immunohistochemistry may be reliably performed on alcohol-fixed, Papanicolaou-stained direct smears.

    2. Efficiency of EGFR mutation analysis for small microdissected cytological specimens using multitech DNA extraction solution (pages 401–412)

      Seo Young Oh and Hoon Taek Lee

      Article first published online: 11 MAY 2015 | DOI: 10.1002/cncy.21550

      The MultiTech DNA extraction solution is a reliable medium that improves the resolution of cell morphology during microdissection. The results of the current study indicate that it is particularly useful in epidermal growth factor receptor mutations of samples containing a small number of cells.

    3. You have free access to this content
      Multiplex sequencing for EZH2, CD79B, and MYD88 mutations using archival cytospin preparations from B-cell non-Hodgkin lymphoma aspirates previously tested for MYC rearrangement and IGH/BCL2 translocation (pages 413–420)

      Gilda da Cunha Santos, Mauro Ajaj Saieg, Hyang Mi Ko, William R. Geddie, Scott L. Boerner, Kenneth J. Craddock, Michael Crump and Denis Bailey

      Article first published online: 23 MAR 2015 | DOI: 10.1002/cncy.21535

      Cytospin preparations (CP) stored at −20°C for up to 6 years are a reliable source of high-quality genomic material for multiplex sequencing. Successful detection of EZH2 (Y641), CD79B (Y196), and MYD88 (L265) mutations can be achieved using material scraped from archival CP obtained from B-cell non-Hodgkin lymphoma aspirates of cases previously tested for MYC rearrangement and IGH/BCL2 translocation.

    4. History of high-risk HPV and Pap test results in a large cohort of patients with invasive cervical carcinoma: Experience from the largest women's hospital in China (pages 421–427)

      Xiang Tao, Christopher C. Griffith, Xiangrong Zhou, Zhiheng Wang, Yabin Yan, Zaibo Li and Chengquan Zhao

      Article first published online: 8 MAY 2015 | DOI: 10.1002/cncy.21545

      In the current study, the authors explore prior high-risk human papillomavirus and Papanicolaou testing within 1 year of the diagnosis of cervical cancer in the largest women's hospital in China. Both high-risk human papillomavirus testing and Papanicolaou cytology appear to have similar negative rates in this population and fewer women were found to have negative testing results with both testing modalities.

    5. Prior high-risk HPV testing and Pap test results for 427 invasive cervical cancers in China's largest CAP-certified laboratory (pages 428–434)

      Baowen Zheng, Zaibo Li, Christopher C. Griffith, Shanshan Yan, Congde Chen, Xiangdong Ding, Xiaoman Liang, Huaitao Yang and Chengquan Zhao

      Article first published online: 8 MAY 2015 | DOI: 10.1002/cncy.21557

      This large study from China investigates prior human papillomavirus and Papanicolaou test results for patients with invasive cervical carcinoma from a population of women without access to an established screening program. The data demonstrate a considerable prior high-risk human papillomavirus–negative rate and a lower prior Papanicolaou-negative rate for these patients.

    6. Non-16/18 high-risk HPV infection predicts disease persistence and progression in women with an initial interpretation of LSIL (pages 435–442)

      Yasmin A. Lyons, Aparna A. Kamat, Haijun Zhou, Dina R. Mody, Mary R. Schwartz, Christopher Hobday and Yimin Ge

      Article first published online: 22 APR 2015 | DOI: 10.1002/cncy.21549

      Non-16/18 high-risk human papillomavirus genotypes strongly predict persistent cervical lesions and progression to high-grade lesions in women with an initial cytology interpretation of a low-grade squamous intraepithelial lesion.

  6. Erratum

    1. Top of page
    2. Issue Information
    3. CytoSource
    4. Clinician's Corner
    5. Commentary
    6. Original Articles
    7. Erratum
    1. You have free access to this content

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