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Heterogeneous expression of SNAP-25 in rat and human brain

  1. Rita Garbelli1,
  2. Francesca Inverardi1,
  3. Valentina Medici1,
  4. Alida Amadeo2,
  5. Claudia Verderio3,
  6. Michela Matteoli3,4,
  7. Carolina Frassoni1,*

Article first published online: 27 NOV 2007

DOI: 10.1002/cne.21589

Issue

The Journal of Comparative Neurology

The Journal of Comparative Neurology

Volume 506, Issue 3, page spc1, 20 January 2008

Additional Information

How to Cite

Garbelli, R., Inverardi, F., Medici, V., Amadeo, A., Verderio, C., Matteoli, M. and Frassoni, C. (2008), Heterogeneous expression of SNAP-25 in rat and human brain. J. Comp. Neurol., 506: spc1. doi: 10.1002/cne.21589

Author Information

  1. 1

    Clinical Epileptology and Experimental Neurophysiology Unit, Fondazione I.R.C.C.S., Istituto Neurologico “C. Besta”, via Celoria 11, Milano, Italy

  2. 2

    Department of Biomolecular Sciences and Biotechnology, University of Milano, via Celoria 26, Milano, Italy

  3. 3

    Department of Medical Pharmacology, CNR Institute of Neuroscience, University of Milano, via Vanvitelli 32, Milano, Italy

  4. 4

    I.R.C.C.S. Don Gnocchi, Milano, Italy

*Clinical Epileptology and Experimental Neurophysiology Unit, Fondazione I.R.C.C.S., Istituto Neurologico “C. Besta”, via Celoria 11, 20133 Milano, Italy

Publication History

  1. Issue published online: 27 NOV 2007
  2. Article first published online: 27 NOV 2007

Funded by

  • Italian Ministry of Health. Grant Number: Ricerca corrente Linea 1.2
  • Telethon. Grant Number: GGP04196
  • European Community Eusynapse
  • Italian University and Health Ministries. Grant Numbers: COFIN 2005, 2005051177_002, FISR 16/10/2000

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Abstract

Confocal laser scanning microscope image of double-labeling immunohistochemistry for SNAP-25 (green) and v-GAT (magenta) in the rat somatosensory cortex. SNAP-25 immunoreactivity was undetectable in inhibitory terminals identified by v-GAT antibody both scattered in the neuropil and clustered around unlabeled neurons. Golgi-like SNAP-25 immunoreactivity was rarely seen in unlabeled large pyramidal neurons. J. Comp. Neurol. 506:373–386, 2008. © 2007 Wiley-Liss, Inc.

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