The first two authors contributed equally.
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Leptin targets in the mouse brain
Article first published online: 23 FEB 2009
DOI: 10.1002/cne.22025
Copyright © 2009 Wiley-Liss, Inc.
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Scott, M. M., Lachey, J. L., Sternson, S. M., Lee, C. E., Elias, C. F., Friedman, J. M. and Elmquist, J. K. (2009), Leptin targets in the mouse brain. J. Comp. Neurol., 514: 518–532. doi: 10.1002/cne.22025
Publication History
- Issue published online: 6 APR 2009
- Article first published online: 23 FEB 2009
- Accepted manuscript online: 23 FEB 2009 12:00AM EST
- Manuscript Accepted: 4 FEB 2009
- Manuscript Revised: 8 AUG 2008
- Manuscript Received: 15 JUN 2007
Funded by
- National Institutes of Heath. Grant Numbers: DK056116, MH061583, DK053301, DK062656
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- 1, , , , , , , , Challenges and Opportunities of Defining Clinical Leptin Resistance, Cell Metabolism, 2012, 15, 2, 150
- 2
- 3, , , Competing clocks: Metabolic status moderates signals from the master circadian pacemaker, Neuroscience & Biobehavioral Reviews, 2012, 36, 1, 254
- 4, , , , , , , , , , , , Direct leptin action on POMC neurons regulates glucose homeostasis and hepatic insulin sensitivity in mice, Journal of Clinical Investigation, 2012,
- 5, , , , Feed-forward mechanisms: Addiction-like behavioral and molecular adaptations in overeating, Frontiers in Neuroendocrinology, 2012,
- 6, , , , , , , , , Functional implications of limited leptin receptor and ghrelin receptor coexpression in the brain, The Journal of Comparative Neurology, 2012, 520, 2Direct Link:
- 7
- 8
- You have free access to this content9, , , Central nervous control of energy and glucose balance: focus on the central melanocortin system, Annals of the New York Academy of Sciences, 2011, 1243, 1Direct Link:
- 10, , Expanding neurotransmitters in the hypothalamic neurocircuitry for energy balance regulation, Protein & Cell, 2011, 2, 10, 800
- 11, , , , , , , , , Hcrtr1 and 2 signaling differentially regulates depression-like behaviors, Behavioural Brain Research, 2011, 222, 2, 289
- 12, , , , , , , Hippocampal Leptin Signaling Reduces Food Intake and Modulates Food-Related Memory Processing, Neuropsychopharmacology, 2011, 36, 9, 1859
- 13, , , , Hypothalamic Sites of Leptin Action Linking Metabolism and Reproduction, Neuroendocrinology, 2011, 93, 1, 9
- 14, , , , , , , , , , Impairment of Central Leptin-Mediated PI3K Signaling Manifested as Hepatic Steatosis Independent of Hyperphagia and Obesity, Cell Metabolism, 2011, 14, 6, 791
- 15, , , , Induction of Leptin Resistance by Activation of cAMP-Epac Signaling, Cell Metabolism, 2011, 13, 3, 331
- 16, Lateral thinking about leptin: A review of leptin action via the lateral hypothalamus, Physiology & Behavior, 2011, 104, 4, 572
- 17, , , , , , Leptin Action on GABAergic Neurons Prevents Obesity and Reduces Inhibitory Tone to POMC Neurons, Neuron, 2011, 71, 1, 142
- 18, , Leptin and the brain, Hormone Molecular Biology and Clinical Investigation, 2011, 7, 2, 351
- 19, , , , , , , , , , , , , , , , Leptin Does Not Directly Affect CNS Serotonin Neurons to Influence Appetite, Cell Metabolism, 2011, 13, 5, 584
- 20, , , , , Leptin receptor expression in hindbrain Glp-1 neurons regulates food intake and energy balance in mice, Journal of Clinical Investigation, 2011, 121, 6, 2413
- 21, , , , Leptin restores adult hippocampal neurogenesis in a chronic unpredictable stress model of depression and reverses glucocorticoid-induced inhibition of GSK-3β/β-catenin signaling, Molecular Psychiatry, 2011,
- 22, , , , , , , , , , , , , , , , , Leptin’s effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons, Journal of Clinical Investigation, 2011, 121, 1, 355
- 23, , , , , , , Metabolic gene expression changes in the hippocampus of obese epileptic male rats in the pilocarpine model of temporal lobe epilepsy, Brain Research, 2011, 1426, 86
- 24, , , , Molecular mapping of mouse brain regions innervated by leptin receptor-expressing cells, Brain Research, 2011, 1378, 18
- You have free access to this content25, Obesity, leptin, and Alzheimer's disease, Annals of the New York Academy of Sciences, 2011, 1243, 1Direct Link:
- 26, , , , Peptidergic Edinger–Westphal neurons and the energy-dependent stress response, General and Comparative Endocrinology, 2011,
- 27, Pivotal role of leptin-hypothalamus signaling in the etiology of diabetes uncovered by gene therapy: a new therapeutic intervention?, Gene Therapy, 2011, 18, 4, 319
- 28, , , , , Selective deletion of the leptin receptor in dopamine neurons produces anxiogenic-like behavior and increases dopaminergic activity in amygdala, Molecular Psychiatry, 2011, 16, 10, 1024
- 29, , , , , , Serotonin 2C Receptor Activates a Distinct Population of Arcuate Pro-opiomelanocortin Neurons via TRPC Channels, Neuron, 2011, 71, 3, 488
- 30, , , , , , SF-1 in the ventral medial hypothalamic nucleus: A key regulator of homeostasis, Molecular and Cellular Endocrinology, 2011, 336, 1-2, 219
- 31, , Sixteen years and counting: an update on leptin in energy balance, Journal of Clinical Investigation, 2011, 121, 6, 2087
- 32, , , , , , , , , Steroidogenic factor 1 directs programs regulating diet-induced thermogenesis and leptin action in the ventral medial hypothalamic nucleus, Proceedings of the National Academy of Sciences, 2011, 108, 26, 10673
- 33, , , , , Subcellular distribution of connexin45 in OFF bipolar cells of the mouse retina, The Journal of Comparative Neurology, 2011, 519, 3Direct Link:
- 34, , , , , Alzheimer's disease: brain expression of a metabolic disorder?, Trends in Endocrinology & Metabolism, 2010, 21, 9, 537
- 35
- 36, , Central leptin signalling: Beyond the arcuate nucleus, Autonomic Neuroscience, 2010, 156, 1-2, 8
- You have free access to this content37, , CNS leptin and insulin action in the control of energy homeostasis, Annals of the New York Academy of Sciences, 2010, 1212, 1Direct Link:
- 38, , , , Co-localization of TRHR1 and LepRb receptors on neurons in the hindbrain of the rat, Brain Research, 2010, 1355, 70
- 39, , , , , , , , , Differential gene expression between neuropeptide Y expressing neurons of the dorsomedial nucleus of the Hypothalamus and the Arcuate Nucleus: Microarray Analysis Study, Brain Research, 2010, 1350, 139
- 40, , , , , , , , , , , , , Distribution and neurochemical characterization of protein kinase C-theta and -delta in the rodent hypothalamus, Neuroscience, 2010, 170, 4, 1065
- You have free access to this content41, , , , , Identifying the efferent projections of leptin-responsive neurons in the dorsomedial hypothalamus using a novel conditional tracing approach, The Journal of Comparative Neurology, 2010, 518, 11Direct Link:
- 42, , , , , Innervation of skeletal muscle by leptin receptor-containing neurons, Brain Research, 2010, 1345, 146
- 43, , , , , , , , , , Leptin-dependent serotonin control of appetite: temporal specificity, transcriptional regulation, and therapeutic implications, Journal of Experimental Medicine, 2010, 208, 1, 41
- 44, , Leptin-sensitive neurons in mouse preoptic area express α1A- and α2A-adrenergic receptor isoforms, Neuroscience Letters, 2010, 471, 2, 83
- 45, , , , , , Melanocortin-4 receptor expression in a vago-vagal circuitry involved in postprandial functions, The Journal of Comparative Neurology, 2010, 518, 1Direct Link:
- 46, , , , , , , The metabolic phenotype of SCD1-deficient mice is independent of melanin-concentrating hormone, Peptides, 2010, 31, 1, 123
- 47, , The two faces of serotonin in bone biology, The Journal of Cell Biology, 2010, 191, 1, 7
- 48, , , , , , Acute administration of leptin produces anxiolytic-like effects: a comparison with fluoxetine, Psychopharmacology, 2009, 207, 4, 535
- 49, , , , , , , , , , , Fluorescent Arc/Arg3.1 indicator mice: A versatile tool to study brain activity changes in vitro and in vivo, Journal of Neuroscience Methods, 2009, 184, 1, 25