Projections of the superior colliculus to the pulvinar in prosimian galagos (Otolemur garnettii) and VGLUT2 staining of the visual pulvinar
Article first published online: 18 MAR 2013
Copyright © 2012 Wiley Periodicals, Inc.
Journal of Comparative Neurology
Volume 521, Issue 7, pages 1664–1682, 1 May 2013
How to Cite
Baldwin, M. K.L., Balaram, P. and Kaas, J. H. (2013), Projections of the superior colliculus to the pulvinar in prosimian galagos (Otolemur garnettii) and VGLUT2 staining of the visual pulvinar. J. Comp. Neurol., 521: 1664–1682. doi: 10.1002/cne.23252
- Issue published online: 18 MAR 2013
- Article first published online: 18 MAR 2013
- Accepted manuscript online: 1 NOV 2012 08:50AM EST
- Manuscript Accepted: 25 OCT 2012
- Manuscript Revised: 23 JUL 2012
- Manuscript Received: 25 MAY 2012
- National Eye Institute. Grant Numbers: RO1 EY-02686, CORE grants P30 EY-008126
- visual system;
An understanding of the organization of the pulvinar complex in prosimian primates has been somewhat elusive due to the lack of clear architectonic divisions. In the current study we reveal features of the organization of the pulvinar complex in galagos by examining superior colliculus (SC) projections to this structure and comparing them with staining patterns of the vesicular glutamate transporter, VGLUT2. Cholera toxin subunit β (CTB), Fluoro-ruby (FR), and wheat germ agglutinin conjugated with horseradish peroxidase (WGA-HRP) were placed in topographically different locations within the SC. Our results showed multiple topographically organized patterns of projections from the SC to several divisions of the pulvinar complex. At least two topographically distributed projections were found within the lateral region of the pulvinar complex, and two less obvious topographical projection patterns were found within the caudomedial region, in zones that stain darkly for VGLUT2. The results, considered in relation to recent observations in tree shrews and squirrels, suggest that parts of the organizational scheme of the pulvinar complex in primates are present in rodents and other mammals. J. Comp. Neurol. 521:1664–1682, 2013. © 2012 Wiley Periodicals, Inc.