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Article
Synaptic organization of cholinergic amacrine cells in the rhesus monkey retina
Article first published online: 9 OCT 2004
DOI: 10.1002/cne.902670209
Copyright © 1988 Alan R. Liss, Inc.
1096-9861/asset/cover.gif?v=1&s=2642f598baa3ea29c6119ef7bbd2b88f473475ce "The Journal of Comparative Neurology")
Additional Information
How to Cite
Mariani, A. P. and Hersh, L. B. (1988), Synaptic organization of cholinergic amacrine cells in the rhesus monkey retina. The Journal of Comparative Neurology, 267: 269–280. doi: 10.1002/cne.902670209
Publication History
- Issue published online: 9 OCT 2004
- Article first published online: 9 OCT 2004
- Manuscript Accepted: 21 JUL 1987
- Abstract
- References
- Cited By
Keywords:
- choline acetyltransferase;
- immunohistochemistry;
- primate retina;
- electron microscopy;
- synapses
Abstract
In the rhesus monkey retina, choline acetyltransferase (ChAT) immunoreactivity has been used to study the localization and synaptic organization of cholinergic neurons by both light and electron microscopy with peroxidase-antiperoxidase immunohistochemistry. ChAT-containing neurons are a type of amacrine cell with 97.5% of their cell bodies localized to the ganglion cell layer and the remainder in the inner nuclear layer. Their processes arborize in a single narrow band in the inner plexiform layer in a plane diving the outer two-thirds from the inner one-third of this synaptic region. With electron microscopy, ChAT-immunoreactive amacrine cell processes were observed to be primarily postsynaptic to the diffuse invaginating cone bipolar cells and presynaptic to ganglion cells, although they are both post- and presynaptic to immunohistochemically unlabeled amacrine cell profiles and to ChAT-containing amacrine cell processes as well.