Central trajectories of type II spiral ganglion neurons
Article first published online: 9 OCT 2004
Copyright © 1988 Alan R. Liss, Inc.
Journal of Comparative Neurology
Volume 278, Issue 4, pages 581–590, 22 December 1988
How to Cite
Brown, M. C., Berglund, A. M., Kiang, N. Y. S. and Ryugo, D. K. (1988), Central trajectories of type II spiral ganglion neurons. J. Comp. Neurol., 278: 581–590. doi: 10.1002/cne.902780409
- Issue published online: 9 OCT 2004
- Article first published online: 9 OCT 2004
- Manuscript Accepted: 29 JUN 1988
- cochlear nucleus granule cell;
- auditory nerve;
- outer hair cell;
- unmyelinated afferent
Previous attempts to trace the central pathways of the thin axons from type II spiral ganglion neurons have been hampered by technical difficulties such as fading of the reaction product as distance increases from the injection site (Ryugo et al.: Soc. Neurosci. Abstr. 12:779, '86; Brown: J. Comp. Neurol. 260:591–604, '87). By using small rodents (gerbils and mice), which have short auditory nerves, we have succeeded in filling the entire central axon and terminals of type II neurons after peripheral injections of horseradish peroxidase. The general course of the type II fibers within the auditory nerve and cochlear nucleus is similar to that of type I fibers except that terminals from type II neurons are often found in regions of the cochlear nucleus that have high densities of granule cells.