Expression of kisspeptins in the brain and pituitary of the european sea bass (Dicentrarchus labrax) (pages 933–948)
Sebastián Escobar, Alicia Felip, Marie-Madeleine Gueguen, Silvia Zanuy, Manuel Carrillo, Olivier Kah and Arianna Servili
Article first published online: 22 JAN 2013 | DOI: 10.1002/cne.23211
Kisspeptins are now considered as major actors in the neuroendocrine control of puberty and reproduction, at least in mammals. Most teleost fishes have two kiss genes, kiss1 and kiss2, but their respective functions in reproduction are still unclear. Thus, it is important to study the distribution of kiss1 and kiss2 expressing cells in the brain and to see which populations are subject to change in expression over the sex cycle. In the European sea bass, an economically important fish, we show that kiss1 expressing cells in the mediobasal hypothalamus show clear changes in expression in mature males and females. These data suggest a role for Kiss1 in reproduction of the sea bass. In addition, kiss1 mRNAs were expressed in FSHβ positive cells and never in LHβ positive cells of the pituitary level.