• cardiovascular fluid mechanics;
  • cerebral aneurysms;
  • fluid–structure interactions;
  • space–time methods;
  • special techniques


We provide an extensive overview of the core and special techniques developed earlier by the Team for Advanced Flow Simulation and Modeling (T★AFSM) for space–time fluid–structure interaction (FSI) modeling of patient-specific cerebral aneurysms. The core FSI techniques are the Deforming-Spatial-Domain/Stabilized Space–Time (DSD/SST) formulation and the stabilized space–time FSI (SSTFSI) technique. The special techniques include techniques for calculating an estimated zero-pressure (EZP) arterial geometry, a special mapping technique for specifying the velocity profile at an inflow boundary with non-circular shape, techniques for using variable arterial wall thickness, mesh generation techniques for building layers of refined fluid mechanics mesh near the arterial walls, a recipe for pre-FSI computations that improve the convergence of the FSI computations, the Sequentially-Coupled Arterial FSI (SCAFSI) technique and its multiscale versions, techniques for the projection of fluid–structure interface stresses, calculation of the wall shear stress (WSS) and calculation of the oscillatory shear index (OSI) and arterial-surface extraction and boundary condition techniques. We show how these techniques work with results from earlier computations. We also describe the arterial FSI techniques developed and implemented recently by the T★AFSM and present a sample from a wide set of patient-specific cerebral-aneurysm models we computed recently. Copyright © 2011 John Wiley & Sons, Ltd.