The preliminary results of this work were presented at the first meeting of ESPRC Patient-Specific Modelling Network in Swansea University, April 2011.
Patient-specific computational biomechanics of the brain without segmentation and meshing†
Version of Record online: 25 AUG 2012
Copyright © 2012 John Wiley & Sons, Ltd.
International Journal for Numerical Methods in Biomedical Engineering
Special Issue: Patient Specific Modelling
Volume 29, Issue 2, pages 293–308, February 2013
How to Cite
Zhang, J. Y., Joldes, G. R., Wittek, A. and Miller, K. (2013), Patient-specific computational biomechanics of the brain without segmentation and meshing. Int. J. Numer. Meth. Biomed. Engng., 29: 293–308. doi: 10.1002/cnm.2507
- Issue online: 5 FEB 2013
- Version of Record online: 25 AUG 2012
- Manuscript Accepted: 20 JUL 2012
- Manuscript Revised: 24 JUN 2012
- Manuscript Received: 15 MAR 2012
- National Health and Medical Research Council. Grant Number: 1006031
- Australian Research Council. Grant Numbers: DP1092893, DP120100402
- patient specific modelling;
- fuzzy mesh-free algorithms;
Motivated by patient-specific computational modelling in the context of image-guided brain surgery, we propose a new fuzzy mesh-free modelling framework. The method works directly on an unstructured cloud of points that do not form elements so that mesh generation is not required. Mechanical properties are assigned directly to each integration point based on fuzzy tissue classification membership functions without the need for image segmentation. Geometric integration is performed over an underlying uniform background grid. The verification example shows that, while requiring no hard segmentation and meshing, the proposed model gives, for all practical purposes, equivalent results to a finite element model. Copyright © 2012 John Wiley & Sons, Ltd.