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Patient-specific computational biomechanics of the brain without segmentation and meshing


  • The preliminary results of this work were presented at the first meeting of ESPRC Patient-Specific Modelling Network in Swansea University, April 2011.

Correspondence to: Karol Miller, Intelligent Systems for Medicine Laboratory, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia.



Motivated by patient-specific computational modelling in the context of image-guided brain surgery, we propose a new fuzzy mesh-free modelling framework. The method works directly on an unstructured cloud of points that do not form elements so that mesh generation is not required. Mechanical properties are assigned directly to each integration point based on fuzzy tissue classification membership functions without the need for image segmentation. Geometric integration is performed over an underlying uniform background grid. The verification example shows that, while requiring no hard segmentation and meshing, the proposed model gives, for all practical purposes, equivalent results to a finite element model. Copyright © 2012 John Wiley & Sons, Ltd.

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