International Journal for Numerical Methods in Biomedical Engineering

Cover image for Vol. 30 Issue 3

March 2014

Volume 30, Issue 3

Pages 297–445

  1. Special Issue Paper - Numerical Methods and Applications of Multi-Physics in Biomechanical Modeling

    1. Top of page
    2. Special Issue Paper - Numerical Methods and Applications of Multi-Physics in Biomechanical Modeling
    3. Paper Presented at Eccomas-3MBM - Multiscale and Multiphysics Modelling in Bone Mechanobiology
    4. Research Articles
    5. Paper Presented at WCCM 2012 - 10th World Congress on Computational Mechanics
    6. Research Articles
    1. Numerical investigation of biomagnetic fluids in circular ducts (pages 297–317)

      K. Tzirakis, Y. Papaharilaou, D. Giordano and J. Ekaterinaris

      Version of Record online: 7 OCT 2013 | DOI: 10.1002/cnm.2603

      Thumbnail image of graphical abstract

      >This paper investigates the biofluid response in the presence of external magnetic fields. To demonstrate the effects, we consider the case of laminar, incompressible, viscous, steady, and pulsatile flow of a Newtonian biofluid through circular ducts. It is shown that rotational magnetic fields characterized by strong spatial gradients deviate the flow significantly even at moderate field strengths. On the other hand, time independent irrotational magnetic fields generate forces that alter the pressure distribution only, leaving the kinematic part unaffected.

  2. Paper Presented at Eccomas-3MBM - Multiscale and Multiphysics Modelling in Bone Mechanobiology

    1. Top of page
    2. Special Issue Paper - Numerical Methods and Applications of Multi-Physics in Biomechanical Modeling
    3. Paper Presented at Eccomas-3MBM - Multiscale and Multiphysics Modelling in Bone Mechanobiology
    4. Research Articles
    5. Paper Presented at WCCM 2012 - 10th World Congress on Computational Mechanics
    6. Research Articles
    1. Multiscale approach including microfibril scale to assess elastic constants of cortical bone based on neural network computation and homogenization method (pages 318–338)

      Abdelwahed Barkaoui, Abdessalem Chamekh, Tarek Merzouki, Ridha Hambli and Ali Mkaddem

      Version of Record online: 7 OCT 2013 | DOI: 10.1002/cnm.2604

      Thumbnail image of graphical abstract

      In this paper, a novel multiscale hierarchical approach including microfibril scale based on hybrid neural network computation and homogenization equations was developed to link nanoscopic and macroscopic scales to estimate the elastic properties of human cortical bone. Our findings of the lowest scale's output were well integrated with the other higher levels and serve as inputs for the next higher scale modeling. Good agreement was obtained between our predicted results and literature data.

  3. Research Articles

    1. Top of page
    2. Special Issue Paper - Numerical Methods and Applications of Multi-Physics in Biomechanical Modeling
    3. Paper Presented at Eccomas-3MBM - Multiscale and Multiphysics Modelling in Bone Mechanobiology
    4. Research Articles
    5. Paper Presented at WCCM 2012 - 10th World Congress on Computational Mechanics
    6. Research Articles
    1. Finite element methods to analyze helical stent expansion (pages 339–352)

      Nasim Paryab, Duane S. Cronin and Pearl Lee-Sullivan

      Version of Record online: 9 OCT 2013 | DOI: 10.1002/cnm.2605

      Thumbnail image of graphical abstract

      Helical stents often experience nonuniform local expansion (dog boning), which can prohibit full stent expansion using conventional methods. A coupled stent-balloon finite element model, although computationally expensive, was able to demonstrate the expected nonuniform deformation. To address nonuniform expansion, a progressive expansion approach has been investigated and verified numerically. This method may also provide a suitable solution for nonuniform expansion in other stent designs by minimizing loading and potential damage to the artery that can occur during stent deployment.

    2. 3D Numerical modeling and its experimental verifications for an inhomogeneous head phantom using broadband fNIR system (pages 353–364)

      E. Sultan, K. Pourrezaei, A. Ghandjbakhche and A.S. Daryoush

      Version of Record online: 20 NOV 2013 | DOI: 10.1002/cnm.2606

      Thumbnail image of graphical abstract

      Modeling behavior of broadband (30-1000 MHZ) frequency modulated near infrared photons through a multilayer phantom is of interest to optical bio-imaging research. Photon dynamics in phantom are predicted using 3D finite element numerical simulation and are related to the experimentally measured insertion loss and phase for a given human head geometry in this paper based on three layers of phantom each with distinct optical parameter properties.

    3. GPU-based acceleration of computations in nonlinear finite element deformation analysis (pages 365–381)

      Ramin Mafi and Shahin Sirouspour

      Version of Record online: 24 OCT 2013 | DOI: 10.1002/cnm.2607

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      Nonlinear FEM for simulating biological soft tissue is computationally demanding. In this paper, we propose a graphic processing unit-based implementation of the FEM using implicit time integration for dynamic nonlinear deformation analysis. The speedup achieved with the proposed parallel implementation of the algorithms will be instrumental in the development of advanced surgical simulators and medical image registration methods involving soft-tissue deformation.

    4. Robust surface reconstruction of teeth from raw pointsets (pages 382–396)

      Zhihong Mao, Kyusic Park, Kunwoo Lee and Xiongbing Li

      Version of Record online: 5 DEC 2013 | DOI: 10.1002/cnm.2608

      Thumbnail image of graphical abstract

      In this paper, a framework for robust 3D dental reconstruction from unorganized noisy scan data to well-aligned, accurate, and smooth surface is presented. Traditional reconstruction process including mesh generation, surface registration, and surface merging induces a large amount of noise accumulated in the dental model. By combining the smallest univalue segment assimilating nucleus (SUSAN) filtering technique with the surface attraction technique, we could not only suppress the noise but also improve the accuracy of the reconstructed mesh.

    5. Development and validation of two subject-specific finite element models of human head against three cadaveric experiments (pages 397–415)

      Kwong Ming Tse, Long Bin Tan, Shu Jin Lee, Siak Piang Lim and Heow Pueh Lee

      Version of Record online: 5 NOV 2013 | DOI: 10.1002/cnm.2609

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      Two finite element head models have been developed and validated against experimental tests. In general, both the simulated results are in reasonably good agreement with the experimental measured intracranial pressure and relative displacements, despite slight discrepancy in a few neutral density targets markers. Sensitivity analysis showed variations in the brain's relative motion to the material properties and marker's location. Little evident differences in predicted responses between the two models suggest traumatic brain injury can be modeled using simplified model.

  4. Paper Presented at WCCM 2012 - 10th World Congress on Computational Mechanics

    1. Top of page
    2. Special Issue Paper - Numerical Methods and Applications of Multi-Physics in Biomechanical Modeling
    3. Paper Presented at Eccomas-3MBM - Multiscale and Multiphysics Modelling in Bone Mechanobiology
    4. Research Articles
    5. Paper Presented at WCCM 2012 - 10th World Congress on Computational Mechanics
    6. Research Articles
    1. Studying the influence of hydrogel injections into the infarcted left ventricle using the element-free Galerkin method (pages 416–429)

      D. Legner, S. Skatulla, J. MBewu, R. R. Rama, B. D. Reddy, C. Sansour, N. H. Davies and T. Franz

      Version of Record online: 26 DEC 2013 | DOI: 10.1002/cnm.2610

      Thumbnail image of graphical abstract

      Myocardial infarction is an increasing health problem worldwide, and intensive research efforts aim to develop new therapies, which ideally lead to full recovery or at least stabilize and support the healing process. The objective of the present investigation is to study the injection therapy, in particular the influence of hydrogel injections into an infarcted left ventricle. Representative values for the cavity pressure and volume, stress and strain are compared for the cases of a healthy, infarcted and injected left ventricle.

  5. Research Articles

    1. Top of page
    2. Special Issue Paper - Numerical Methods and Applications of Multi-Physics in Biomechanical Modeling
    3. Paper Presented at Eccomas-3MBM - Multiscale and Multiphysics Modelling in Bone Mechanobiology
    4. Research Articles
    5. Paper Presented at WCCM 2012 - 10th World Congress on Computational Mechanics
    6. Research Articles
    1. Effects of the ambient temperature on the airflow across a Caucasian nasal cavity (pages 430–445)

      M.A. Burgos, E. Sanmiguel-Rojas, A. Martín-Alcántara and M. Hidalgo-Martínez

      Version of Record online: 5 DEC 2013 | DOI: 10.1002/cnm.2616

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      We analyse the effects of the air ambient temperature on the airflow across a Caucasian nasal cavity using CFD simulations. We find an excellent linear relationship between the ambient temperature and the air average temperature reached at different cross sections, independently of the pressure drop applied. Moreover, the spatial evolution of the mean temperature along the cavity can be fitted by hyperbolic functions, and the fittings collapse for all ambient temperatures analysed with the introduction of suitable dimensionless variables.

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