Within the framework of our series of experiments, 16 artists made judgments on the harmony content of color compositions using two different methods. First, using the traditionally accepted method, at natural daylight, with their eyes adapted to light, they judged the compositions. Following that, they used, the nowadays more popular, instrumental simulation of the experimental color objects. The second part of the experiment was performed in a dark room and the subjects had their eyes adapted to dark, before the experiment. According to the outcome of these experiments, the results were substantially different. These differences were recorded in diagrams and formulated in mathematical form. Our conclusion, based on these results, is that the simulated experimental results cannot be used for the description of the harmony content between colors at natural conditions. The importance of these results has strong relevance to the judgment of color harmony between colors on the TV screen. To describe this particular harmony, we need a different word. © 2012 Wiley Periodicals, Inc. Col Res Appl, 38, 448–455, 2013.