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Super-Resolution Imaging of DNA Labelled with Intercalating Dyes

Authors

  • Cristina Flors Dr.,

    1. School of Chemistry and Collaborative Optical Spectroscopy Micromanipulation & Imaging Centre (COSMIC), University of Edinburgh, Joseph Black Building, The King's Buildings, West Mains Rd., EH9 3JJ Edinburgh (United Kingdom), Fax: (+44) (0)131 650 6453
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  • Charles N. J. Ravarani,

    1. School of Chemistry and Collaborative Optical Spectroscopy Micromanipulation & Imaging Centre (COSMIC), University of Edinburgh, Joseph Black Building, The King's Buildings, West Mains Rd., EH9 3JJ Edinburgh (United Kingdom), Fax: (+44) (0)131 650 6453
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  • David. T. F. Dryden Dr.

    1. School of Chemistry and Collaborative Optical Spectroscopy Micromanipulation & Imaging Centre (COSMIC), University of Edinburgh, Joseph Black Building, The King's Buildings, West Mains Rd., EH9 3JJ Edinburgh (United Kingdom), Fax: (+44) (0)131 650 6453
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Abstract

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Imaging DNA: DNA intercalating cyanine dyes provide a simple and convenient method to image DNA topology by means of fluorescence microscopy with a spatial resolution better than the diffraction limit of light (see picture).

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