Sub-Diffraction Imaging of Huntingtin Protein Aggregates by Fluorescence Blink-Microscopy and Atomic Force Microscopy

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Abstract

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Resolving aggregates: Single-molecule super-resolution imaging of fluorescent Huntington′s disease proteins reveals the detailed morphology of aggregates in aqueous environments (see figure, color) and shows excellent agreement with atomic force microscopy images (figure, black) of the same aggregates.

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