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Molecular Confinement in Fluorescent Magnetic Mesoporous Silica Nanoparticles: Effect of Pore Size on Multifunctionality

Authors

  • Jixi Zhang,

    1. School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030 (China)
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  • Dr. Jessica M. Rosenholm,

    1. Laboratory for Physical Chemistry, Department of Natural Sciences, Åbo Akademi University, 3-5 Porthansgatan, Turku, FIN-20500 (Finland)
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  • Prof. Hongchen Gu

    Corresponding author
    1. School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030 (China)
    • School of Biomedical Engineering and Med-X Research Institute, Shanghai Jiao Tong University, 1954 Huashan Road, Shanghai 200030 (China)
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Abstract

original image

Like Swiss cheese: The fabrication of PEG-modified FITC-labeled magnetic mesoporous silica nanoparticles (F-M-MSN) with three different pore sizes is described (see picture). Based on molecular confinement, the effect of pore size on their dual-modal imaging and drug delivery properties is explored.

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