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Keywords:

  • drug delivery;
  • hydrogel;
  • hyperpolarization;
  • NMR spectroscopy;
  • xenon
Thumbnail image of graphical abstract

Welcome to the guest zone: By combining hyperpolarized xenon and simple low-field NMR devices it is possible to obtain more control over hydrogels that show potential as drug delivery systems. An alternative way of polymer swelling-degree determination is demonstrated with real-time NMR analysis. An ideal region for solvent uptake can be defined in which the absorbed solvent molecules are completely confined in the nano-porous network of the hydrogel.